2023 Fiscal Year Final Research Report
Establishment of pH Biology
| Project Area | Establishment of pH Biology |
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| Project/Area Number |
20H05787
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| Research Category |
Grant-in-Aid for Transformative Research Areas (B)
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| Allocation Type | Single-year Grants |
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| Review Section |
Transformative Research Areas, Section (III)
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
栗原 晴子 琉球大学, 理学部, 教授 (40397568)
船戸 洋佑 京都大学, 工学研究科, 准教授 (60505775)
岡村 康司 大阪大学, 大学院医学系研究科, 教授 (80201987)
久保田 好美 独立行政法人国立科学博物館, 地学研究部, 研究主幹 (80710946)
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| Project Period (FY) |
2020-10-02 – 2023-03-31
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| Keywords | pH |
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| Outline of Final Research Achievements |
The greatest achievement lies in establishing a foundation that bridges the significant gap between physiology/medicine and marine biology/evolutionary studies. For instance, through trial and error, we successfully extracted DNA and RNA from the previously deemed impossible source, the Yubieda coral, and became the first in the world to identify its complete genome sequence. Additionally, our outreach efforts, particularly in educating children who are the future, have been vigorous. Examples include hosting public lectures at the National Museum of Nature and Science [attendance: approximately 300 attendees on-site and online combined, including approximately 50 high school students], and organizing a symposium titled '100th Anniversary Symposium' at the Physiology Society Conference. These activities exemplify our commitment to engaging with the public. It appears that we have achieved results beyond expectations in constructing a forward-looking research framework.
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| Free Research Field |
分子生物化学
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| Academic Significance and Societal Importance of the Research Achievements |
本領域は、pH関連生命現象（pH適応機構、pHシグナル）を地球の歴史や生命の進化史という時間軸で俯瞰的に捉えようとするものであり、かつてこれ程までに学際的な広がりを持たせた領域研究は存在しない。本領域がもたらす波及効果は、ヒトを対象とした基礎医学に留まらず、幅広い生物種にとって深刻な問題である海洋酸性化にまで視野に入れたものである。今後さらに海洋だけではなく、大気や温度など気候変動にともなう地球上全ての生命体の適応を、「学術の力」で理解し将来的な解決への道筋を作っていくための、「さきがけ」ともなる。
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