New aspect of the ubiquitin system : its enormous roles in protein regulation

2016 Fiscal Year Final Research Report

• Project Area: New aspect of the ubiquitin system : its enormous roles in protein regulation
• Project/Area Number: 24112001
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Biological Sciences
• Research Institution: Kyoto University
• Principal Investigator: IWAI Kazuhiro 京都大学, 医学研究科, 教授 (60252459)
• Co-Investigator(Kenkyū-buntansha): 駒田 雅之 東京工業大学, 生命理工学研究科, 教授 (10225568) ; 嘉村 巧 名古屋大学, 理学(系)研究科(研究院), 教授 (40333455) ; 佐伯 泰 公益財団法人東京都医学総合研究所, その他部局等, その他 (80462779)
• Project Period (FY): 2012-06-28 – 2017-03-31
• Keywords: 領域内研究者交流 / 情報交換 / 若手支援 / 国際化推進

Outline of Final Research Achievements

Ubiquitin, a proteinous post-translational modifier, has been studied as a part of protein degradation system. However, it is now widely recognized that the ubiquitin system is involved in the regulation of a wide variety of biological phenomena by modulating protein functions in many ways. Since dissection methods of the ubiquitin system become diversified and highly developed, it is almost impossible to do all the dissections in one laboratory. “New aspect of the ubiquitin system : its enormous roles in protein regulation”, an research area of Grant-in-Aid for Scientific Research on Innovative Areas was organized to develop cutting-edge technologies to dissect the ubiquitin system and tried to identify new roles of the ubiquitin system in the regulation of biological phenomena. This research project is a headquarter of the research area and handled advertisement, organizing conference for young as well as foreign researchers and promoting collaborations within research areas.

Free Research Field

生体分子医学