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2019 Fiscal Year Final Research Report

Environmental control of plant cell reprogramming

Planned Research

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Project AreaIntegrative system of autonomous environmental signal recognition and memorization for plant plasticity
Project/Area Number 15H05961
Research Category

Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)

Allocation TypeSingle-year Grants
Review Section Biological Sciences
Research InstitutionInstitute of Physical and Chemical Research

Principal Investigator

SUGIMOTO Keiko  国立研究開発法人理化学研究所, 環境資源科学研究センター, チームリーダー (30455349)

Project Period (FY) 2015-06-29 – 2020-03-31
Keywordsエピジェネティックス / ヒストン修飾 / 細胞リプログラミング / 傷害ストレス / シロイヌナズナ
Outline of Final Research Achievements

Some plant cells in somatic tissues dedifferentiate and redifferentiate in response to various environmental stimuli but molecular mechanisms underlying this control are not well understood. In this study we studied how plants transduce the severe damage signals and modify epigenetic cellular memories to induce cellular reprogramming. We demonstrated that histone acetylation is central to promote cellular reprgramming in plants.

Free Research Field

植物分子遺伝学

Academic Significance and Societal Importance of the Research Achievements

環境刺激によって個々の細胞の記憶が可塑的に制御される分子機構を明らかにすることで、植物の多元的な環境応答システムの理解を進めることができる点に学術的意義がある。これまで再生が困難であった植物種でも、ヒストンのアセチル化を人為的に操作することで効率よく細胞リプログラミングを誘導し、再生しやすくすることが期待される。

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Published: 2021-02-19  

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