Study on Correlation of the Function of Polymer Brushes with the Dynamic Properties of Vicinal Water

2012 Fiscal Year Final Research Report

• Project Area: Molecular Soft-Interface Science
• Project/Area Number: 20106007
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: University of Toyama
• Principal Investigator: KITANO Hiromi 富山大学, 大学院・理工学研究部(工学), 教授 (40115829)
• Co-Investigator(Kenkyū-buntansha): GEMMEI Makoto 富山大学, 理工学研究部(工学), 助教 (70334711)
• Project Period (FY): 2008 – 2012
• Keywords: 高分子物性 / 生体材料 / 表面界面物性

Research Abstract

The interaction between water and polymers largely affects properties of the polymers in solution and solid systems. To clarify the structure of water at polymer-water interfaces, we have examined the structure and orientation of water molecules in the vicinity of polymer thin films and polymer brushes using sum frequency generation (SFG) method which can detect the orientation of molecules at interfaces.

Research Products

• [Journal Article] Biodegradable microparticles for strictly regulating the release of neurotrophic factors (2013)
  • Author(s): Gujral, C.; Minagawa, Y.; Fujimoto, K.; Kitano, H.; Nakaji-Hirabayashi, T
  • Journal Title: J. Control. Release Volume: 168 Pages: 307-316
• [Journal Article] Two-Step Recrystallization of Water in Concentrated Aqueous Solution of Poly(ethylene glycol) (2013)
  • Author(s): Gemmei-Ide, M.; Kasai, R.; Motonaga, T.; Kitano, H
  • Journal Title: J. Phys. Chem. B Volume: 117 Pages: 2188-2194
• [Journal Article] Self-association of zwitterionic polymer-lipid conjugates in water as examined by scattering measurements (2013)
  • Author(s): Murou, M.; Kitano, H.; Fujita, M.; Maeda, M.; Saruwatari, Y
  • Journal Title: J. Colloid Interface Sci Volume: 390 Pages: 47-53
• [Journal Article] Polymer brush with pendent glucosylurea groups constructed on a glass substrate (2012)
  • Author(s): Kitano, H.; Liu, T.; Tokuwa, K.; Li, L.; Iwanaga, S.; Nakamura, M.; Kanayama, N.; Ohno, K.; Saruwatari, Y
  • Journal Title: Eur. Polym. J Volume: 48 Pages: 1875-1882
• [Journal Article] Structure of water in the vicinity of a zwitterionic polymer brush as examined by sum frequency generation method. Kondo (2012)
  • Author(s): Nomura, K.; Murou, M.; Gemmei-Ide, M.; Kitano, H.; Ohno, K.; Noguchi, H.; Uosaki, K.; Saruwatari, Y
  • Journal Title: Colloids Surfaces B: Biointerfaces Volume: 100 Pages: 126-132
• [Journal Article] Carboxymethylbetaine copolymer layer covalently fixed to a glass substrate (2012)
  • Author(s): Suzuki, H.; Li, L.; Nakaji, T.; Kitano, H.; Ohno, K.; Matsuoka. K.; Saruwatari, Y
  • Volume: 94
  • Pages: 107-113
• [Journal Article] Recrystallization of Water in Non-Water-Soluble (Meth)Acrylate Polymers is Not Rare and is Not Devitrification (2012)
  • Author(s): Gemmei-Ide, M.; Ohya, A.; Kitano, H
  • Journal Title: J. Phys. Chem. B Volume: 116 Pages: 1850-1857
• [Journal Article] Binding of β-amyloid to sulfated sugar residues in a polymer brush (2012)
  • Author(s): Kitano, H.; Saito, D.; Kamada, T.; Gemmei-Ide, M
  • Journal Title: Colloids Surfaces B: Biointerfaces Volume: 93 Pages: 219-225
• [Journal Article] Sum frequency generation study on the structure of water in the vicinity of an amphoteric polymer brush (2012)
  • Author(s): Kondo, T.; Gemmei-Ide, M.; Kitano, H.; Ohno, K.; Noguchi, H.; Uosaki, K
  • Journal Title: Colloids Surfaces B: Biointerfaces Volume: 91 Pages: 215-218
• [Journal Article] 固体高分子中の水の結晶化挙動と生体適合性の相関 (2012)
  • Author(s): 源明 誠, 北野博巳
  • Journal Title: 表面科学 Volume: Vol.33 Pages: 15-20
• [Journal Article] Anti-biofouling properties of amphoteric polymer brush constructed on a glass substrate (2011)
  • Author(s): Kitano, H.; Kondo, T.; Iwanaga, S.; Nakamura, M.; Ohno, K
  • Journal Title: Colloids Surfaces B: Biointerfaces Volume: 88 Pages: 455-462
• [Journal Article] Silica particles coated with zwitterionic polymer brush: Formation of colloidal crystals and anti-biofouling properties in aqueous medium (2011)
  • Author(s): Suzuki, H.; Murou, M.; Kitano, H.; Ohno, K.; Saruwatari, Y
  • Journal Title: Colloids Surfaces B: Biointerfacse Volume: 84 Pages: 111-116
• [Journal Article] Image Printing on the Surface of Anti-biofouling Zwitterionic Polymer Brush by Ion Beam Irradiation (2011)
  • Author(s): Kitano, H.; Suzuki, H.; Kondo, T.; Sasaki, K.; Iwanaga, S.; Nakamura, M.; Ohno, K.; Saruwatari, Y
  • Journal Title: Macromol. Biosci Volume: 11 Pages: 557-564
• [Journal Article] 界面科学の基礎 (2011)
  • Author(s): 北野博巳
  • Journal Title: CSJカレントレビュー04 「新しい局面を迎えた界面の分子科学-機能デザインと計測技術の展開」日本化学会編 Pages: 10-16
• [Journal Article] 高分子材料近傍の水の構造と機能との相関 (2011)
  • Author(s): 源明 誠, 北野博巳
  • Journal Title: 未来材料 Volume: Vol.11, No.10 Pages: 40-46
• [Journal Article] Suitability of Synthetic Copolymer Membranes as a Human Skin Alternative for In Vitro Skin Permeation Testing (2010)
  • Author(s): Miki, R.; Kimura, S.; Ueda, H.; Shimamura, T.; Numajiri, S.; Seki, T.; Juni, K.; Kitano, H.; Morimoto, Y
  • Journal Title: Alternatives to Animal Testing and Experimentations (AATEX) Volume: 15 Pages: 14-27
• [Journal Article] Drying dissipative structures of colloidal crystals of silica spheres coated with polymer brushes of poly(carboxymethyl betaine) (2010)
  • Author(s): Okubo, T.; Suzuki, H.; Kitano, H.; Ohno, K.; Mizutani, M.; Tsuchida, A
  • Journal Title: Colloid Polym. Sci Volume: 288 Pages: 1233-1243
• [Journal Article] Direct spectroscopic observation of binding of sugars to polymers having phenylboronic acids substituted with an ortho-phenylazo group (2010)
  • Author(s): Okasaka, Y.; Kitano, H
  • Journal Title: Colloids Surfaces B: Biointerfaces Volume: 79 Pages: 434- 439
• [Journal Article] Thermally Latent Water in a Polymer Matrix (2010)
  • Author(s): Gemmei-Ide, M.; Ohya, A.; Kitano, H
  • Journal Title: J. Phys. Chem. B Volume: 114 Pages: 4310-4312
• [Journal Article] Molecular Recognition at the Exterior Surface of Zwitterionic Telomer Brush (2010)
  • Author(s): Kitano, H.; Kondo, Y. Saito, D.; Gemmei-Ide, M.; Morita, H.; Kanayama, N
  • Journal Title: Colloids Surfaces B: Biointerfaces Volume: 78 Pages: 155-162
• [Journal Article] Temperature-Responsive Polymer Brush Constructed on a Glass Surface by Atom Transfer Radical Polymerization (2010)
  • Author(s): Kitano, H.; Kondo, T.; Suzuki, H.; Ohno, K
  • Journal Title: J. Colloid Interface Sci Volume: 345 Pages: 25-331
• [Journal Article] Correlation between the Function of Polymer Materials and the Structure of Vicinal Water (2010)
  • Author(s): Kitano, H
  • Journal Title: 高分子 Volume: Vol.59 Pages: 69
• [Journal Article] Structure of Water in the Vicinity of Amphoteric Polymers As Revealed by Vibrational Spectroscopy (2010)
  • Author(s): Kitano, H.; Gemmei-Ide, M.
  • Journal Title: J. Biomater. Sci. Polym. Edn Volume: Vol.21 Pages: 1877-1893
• [Journal Article] Dissipative crystallization of aqueous solution of sodium polymethacrylate (2009)
  • Author(s): Okubo, T.; Hagiwara, A.; Kitano, H.; Okamoto, J.; Takahashi, S.; Tsuchida, A
  • Journal Title: Colloid Polymer Sci Volume: 287 Pages: 1155-1165
• [Journal Article] Effect of End Groups of Poly(n-butyl methacrylate) on Its Biocompatibility (2009)
  • Author(s): Fujishita, S.; Inaba, C.; Ishisaka, T.; Gemmei-Ide, M.; Kitano, H
  • Journal Title: Colloids Surfaces B: Biointerfaces Volume: 74 Pages: 45-50
• [Journal Article] Anti-biofouling Property of a Telomer Brush with Pendent Glucosylurea Groups (2009)
  • Author(s): Kitano, H.; Hayashi, A.; Takakura, H.; Suzuki, H.; Kanayama, N.; Saruwatari, Y
  • Journal Title: Langmuir Volume: 25 Pages: 9361-9368
• [Journal Article] Kinetic study on the binding of lectin to mannose residues in a polymer brush (2009)
  • Author(s): Kitano, H.; Takahashi, Y.; Mizukami, K.; Matsuura, K
  • Journal Title: Colloids Surfaces B: Biointerfaces Volume: 70 Pages: 91-97
• [Journal Article] Temperature Responsive Polymer Brush Constructed on a Colloidal Gold Monolayer (2009)
  • Author(s): Kitano, H.; Kago, H.; Matsuura, K
  • Journal Title: J. Colloid Interface Sci Volume: 331 Pages: 343-350
• [Journal Article] Anti-Biofouling Property of Polymers with a Carboxybetaine Moiety (2009)
  • Author(s): Tada, S.; Inaba, C.; Mizukami, K.; Fujishita, S.; Gemmei-Ide, M.; Kitano, H.; Mochizuki, A.; Tanaka, M.; Matsunaga, T
  • Journal Title: Macromol. Biosci Volume: 9 Pages: 63-70
• [Journal Article] 生体適合性と水和 (2009)
  • Author(s): 北野博巳, 源明 誠
  • Journal Title: 高分子 Volume: Vol.58 Pages: 74-77
• [Journal Article] 高分子材料の機能と水和構造の相関 (2008)
  • Author(s): 北野博巳, 源明誠
  • Journal Title: 日本接着学会誌 Volume: Vol.44 Pages: 485-490
• [Book] 温度可変赤外分光法による固体高分子中の水の相転移挙動の評価, 「IR分析に関する技術資料」 (2013)
  • Author(s): 源明誠,北野博巳
  • Total Pages: (発刊予定)
  • Publisher: 株式会社 技術情報協会
• [Book] 双性イオン型高分子シランカップリング剤とその応用, 「シランカップリング剤の効果と使用方法」 (2012)
  • Author(s): 北野博巳, 李黎夫, 中路正
  • Publisher: サイエンス&テクノロジー株式会社
• [Book] Sensing Capabilities of Self-Assembled Monolayer Using Localized Surface Plasmon Resonance Spectroscopy (2009)
  • Author(s): Kitano, H.; Mizukami, K
  • Total Pages: 395-415
  • Publisher: Bottom-Up Nanofabrication: American Scientific Publishers: Vol.3
• [Book] 分光学的解析, 「ソフトマター:分子設計・キャラクタリゼーションから機能性材料まで」 (2009)
  • Author(s): 源明 誠, 北野博巳
  • Total Pages: 127-137
  • Publisher: 丸善
• [Patent(Industrial Property Rights)] 光分解性材料,基板及びそのパターニング方法 (2012)
  • Inventor(s): 北野博巳,中路 正,源明 誠,岸岡高広,木村重雄,広井佳臣,臼井友輝
  • Industrial Property Rights Holder: 国立大学法人富山大学,日産化学工業株式会社
  • Industrial Property Number: 特願、2012-226380
  • Filing Date: 2012-10-11
• [Patent(Industrial Property Rights)] 医療用材料 (2008)
  • Inventor(s): 北野博巳,源明 誠,猿渡欣幸,向山高広
  • Industrial Property Rights Holder: 大阪有機化学工業株式会社
  • Industrial Property Number: 特開、2010-57745
  • Filing Date: 2008-09-04
• [Patent(Industrial Property Rights)] 創傷被覆組成物および創傷被覆材 (2007)
  • Inventor(s): 北野博巳,源明 誠,藤下繁人,猿渡欣幸
  • Industrial Property Rights Holder: テイカ製薬株式会社,大阪有機化学工業株式会社
  • Industrial Property Number: 特開、2008-274151
  • Filing Date: 2007-05-01
• [Patent(Industrial Property Rights)] 医療用材料 (2005)
  • Inventor(s): 北野博巳,源明 誠,猿渡欣幸,向山高広
  • Industrial Property Rights Holder: 大阪有機化学工業株式会社
  • Industrial Property Number: 特開、2007-130194
  • Filing Date: 2005-11-10