Development of Catalytic reactions Involving Activation of Unreactive Bonds

2015 Fiscal Year Final Research Report

• Project Area: Molecule Activation Directed toward Straightforward Synthesis
• Project/Area Number: 22105002
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Osaka University
• Principal Investigator: CHATANI Naoto 大阪大学, 工学(系)研究科(研究院), 教授 (30171953)
• Co-Investigator(Renkei-kenkyūsha): FUKUMOTO Yoshiya 大阪大学, 大学院工学研究科, 准教授 (50273595) ; TOBISU Mamoru 大阪大学, 大学院工学研究科, 准教授 (60403143)
• Project Period (FY): 2010-04-01 – 2016-03-31
• Keywords: 炭素－水素結合活性化 / 炭素－酸素結合活性化 / 炭素－窒素結合活性化 / 炭素－リン結合活性化 / 炭素－硫黄結合活性化

Outline of Final Research Achievements

A new type of C-H functionalization reactions utilizing an N,N-bidentate chelation system has been developed. It was found that Ni/8-aminoquinoline directing group is reliable system for developing the Ni-catalyzed C-H functionalizations. In addition, some catalytic reactions using ruthenium and rhodium chlorides have been successfully developed.
After the examination of the effect of NHC ligands on the efficiency of C-O bond activation, it was found that ICy shows a high catalytic activity. The use of ICy led to the development of new reactions, which cannot achieve by using conventional common ligands.

Free Research Field

有機合成化学