Multiscale modeling of plasma-bio interactions

2016 Fiscal Year Final Research Report

• Project Area: Plasma medical innovation
• Project/Area Number: 24108005
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Toyohashi University of Technology
• Principal Investigator: Mizuno Akira 豊橋技術科学大学, 工学(系)研究科(研究院), シニア研究員 (20144199)
• Co-Investigator(Renkei-kenkyūsha): Toshihiko Eki 豊橋技術科学大学, 大学院工学研究科, 教授 (40192512) ; Hideto Tsuji 豊橋技術科学大学, 大学院工学研究科, 教授 (60227395) ; Kazunori Takashima 豊橋技術科学大学, 大学院工学研究科, 教授 (60303707) ; Hirofumi Kurita 豊橋技術科学大学, 大学院工学研究科, 助教 (70512177) ; Hachiro Yasuda 豊橋技術科学大学, 大学院工学研究科, 助手 (20200503)
• Project Period (FY): 2012-06-28 – 2017-03-31
• Keywords: 大気圧プラズマ / プラズマ医療応用 / プラズマ応用

Outline of Final Research Achievements

Non-Thermal atmospheric pressure Plasma, NTP, has been extensively studied for medical applications, which include sterilization, treatment of wounds and blood coagulation, and cancer therapy. For understanding of the mechanism of plasma treatments for medical applications, the effect of NTP on biomacromolecules, viruses, E. coli, Bacillus subtilis spore, S. celevisiae, human cancer cells, and C. elegance are studied using various method. Our results suggests that reactive species produced in liquids attack cell membrane or cell wall, and then oxidative damage on biomacromolecules are induced, finally various kinds of cellular responses are observed. This framework is common to various model organisms.

Free Research Field

静電気・大気圧プラズマ応用