Rapid and high resolution molecular imaging with stigmatic imaging mass spectrometry

2017 Fiscal Year Final Research Report

• Project Area: Interdisciplinary research on quantum imaging opened with 3D semiconductor detector
• Project/Area Number: 25109009
• Research Category: Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area)
• Allocation Type: Single-year Grants
• Review Section: Science and Engineering
• Research Institution: Osaka University
• Principal Investigator: AWAZU Kunio 大阪大学, 工学研究科, 教授 (30324817)
• Co-Investigator(Kenkyū-buntansha): 間 久直 大阪大学, 工学研究科, 准教授 (70437375) ; 青木 順 大阪大学, 理学(系)研究科(研究院), その他 (90452424)
• Co-Investigator(Renkei-kenkyūsha): TOYODA Michisato 大阪大学, 大学院理学研究科, 教授 (80283828) ; KAWAI Yosuke 大阪大学, 大学院理学研究科, 助教 (90726671)
• Research Collaborator: HONDO Toshinobu ; MATSUOKA Hisanori ; ARAI Yasuo ; FUJITA Yowichi ; IKEBE Masayuki ; TSURUMOTO Yuma ; Nomura SHUSEI ; KAWAI Hayato ; IMOTO Eishi ; OKAZAKI Ayane ; MORIGUCHI Naoki ; KANNEN Hiroki
• Project Period (FY): 2013-06-28 – 2018-03-31
• Keywords: イメージング質量分析 / 投影型 / silicon-on-insulator / 3次元半導体検出器 / 量子イメージング

Outline of Final Research Achievements

A rapid and high resolution molecular imaging device with stigmatic imaging mass spectrometry has been developed. Since a position and time sensitive ion detector is required for practical use of stigmatic imaging mass spectrometry, novel ion detector has been developed with a semiconductor pixel detector. Prototype ion detectors have been developed two times in FY2013, and one time per year from FY2014 to FY2017. Finally, an ion detector with 192 x 192 pixels in 13.75 x 15.3 mm2, its driving circuit, and control software have been developed in FY2017, and its operation at the target time resolution of 1 ns was confirmed.

Free Research Field

レーザー医工学、生体組織光学