1989 Fiscal Year Final Research Report Summary
Epidemiological and immunological study on Behcet's disease in China.
| Project/Area Number |
01044049
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| Research Category |
Grant-in-Aid for international Scientific Research
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| Allocation Type | Single-year Grants |
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| Section | Joint Research |
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| Research Institution | Tokyo Medical & Dental University |
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Principal Investigator |
SAKUMA Akira Professor, Dept. of Clinical Pharmacology, Med. Res. Inst. Tokyo Medical & Dental University, 難治疾患研究所・臨床薬理学部門, 教授 (10013830)
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| Co-Investigator(Kenkyū-buntansha) |
王 珮 北京医科大学人民医院, 薬理学, 付教授
田 丁 北京医科大学人民医院, 内科, 付教授
TSUCHIDA Mitsuru Assistant Professor, Dept. of Social Medicine Tokyo Medical & Dental University, 難治疾患研究所・社会医学研究部門, 助手 (00163824)
MINESHITA Satoru Professor, Dept. of Social Medicine Tokyo Medical & Dental University, 難治疾患研究所・社会医学研究部門, 教授 (00014358)
TANAKA Heizo Professor, Dept. of Social Medicine Tokyo Medical & Dental University, 難治疾患研究所・社会医学研究部門, 教授 (70047215)
DING Tian Associate Professor, People's Hospital, Inst. of Hematology Beijing Medical Univ
PEI Wang Asspcoate Professor, People's Hospital, Inst. of Pharmacology Beijing Medical Un
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| Project Period (FY) |
1989 – 1991
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| Keywords | Behcet's disease / Tianjin / Harbin / Beijing / complete type / incomplete type / HLA-B51 / 遺伝的素因 |
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| Research Abstract |
In this year, our project was carried out on following points:
1. Epidemiological study on the patients in Tianjin in 14 years (1974-1988). The total number was 158, 39 men and 119 women. Patients in their thirties were most common in men and twenties were most common in women. Complete type was 30% in men, 28.6% in women. All patients in incomplete type were lacking eye symptom.
2. Clinical study of patients in Harbin. The total number which was observed in last year (1988-1989) was 41 cases, patients in their thirties were most common in men, and twenties and thirties were most common in women. Complete type was 57% in men, and 37% in women. All patients in incomplete type were lacking eye symptom.
3. A study of HLA antigens in patients in Beijing Medical University. Thirty Chinese Han nationality patients with BD were typed for HLA antigens. The present study revealed that HLA-B51 was significantly increased in the entire group of BD patients.
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