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1991 Fiscal Year Final Research Report Summary

Studies on the pathogenesis of the disturbed integration of functions in both hemispheres of the functional psychoses

Research Project

Project/Area Number 01304040
Research Category

Grant-in-Aid for Co-operative Research (A)

Allocation TypeSingle-year Grants
Research Field Psychiatric science
Research InstitutionKanazawa University

Principal Investigator

YAMAGUCHI Nariyoshi  Kanazawa University School of Medicine Department of Neuropsychiatry Professor, 医学部, 教授 (00064501)

Co-Investigator(Kenkyū-buntansha) KURACHI Masayoshi  Toyama Medical and Pharmaceutical University Department of Neuropsychiatry Profe, 医学部, 教授 (80019603)
TAKAHASHI Saburo  Shiga University of Medical Science Department of Psychiatry and Neurology Profe, 医学部, 教授 (20079916)
NIWA Shin-ichi  Tokyo University Faculty of medicine Department of Neuropsychiatry Instructor, 医学部, 助手 (30110703)
KOJIMA Takuya  Tokyo Medical and Dental University Department of Neuropsychiatry Assistant Prof, 医学部, 講師 (40014203)
SATO Mitsumoto  Tohoku University School of Medicine Department of Neuropsychiatry Professor, 医学部, 教授 (70033321)
Project Period (FY) 1989 – 1990
KeywordsFunctional psychosis / Disturbed integration of functions in both hemispheres / Cognition disorder / Event-related potential / Regional cerebral blood flow / Continent negative variation / Neuroimaging / Eye movements
Research Abstract

The etiology of the functional psychoses such as schizophrenia and mood disorder is not clear. It is assumed that there is the disturbed integration of function in both hemispheres in the functional psychoses. We have tried this research for the purpose to clear the etiology of the functional psychoses by using the neuropsychological, neurophysiological, and neuroimaging methods.
Yamaguchi and Kurachi studied the relationship between frontal blood flow and clinical findings in schizophrenic patients. Compared with the normal controls, the patients showed a reduced relative frontal flow in the left hemisphere. Sato and Kojima investigated the eye fixations and movements during maze test in schizophrenia. Yamauchi investigated an asymmetry of EEG background activity in schizophrenia. Niwa and Machiyama studied the auditory event-related potentials in schizophrenia. Takahashii investigated the CNV in depression. Hozaki and Torn performed neuropsychological investigations on chronic schizophrenia from aspects of its frontal function.

  • Research Products

    (17 results)

All Other

All Publications (17 results)

  • [Publications] 鳥居 方策,北本 福美: "痴呆の神経心理学ー特に言語障害を中心にー" 老年期痴呆研究会誌. 3. 21-26 (1989)

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  • [Publications] 佐藤 光源: "精神分裂病の再発をめぐる諸問題" 日精協雑誌. 9. 12-19 (1990)

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  • [Publications] 山口 成良: "ベンゾジアゼピン依存" 神経精神薬理. 13. 90-94 (1991)

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  • [Publications] 倉知 正佳,湯浅 悟,鈴木 道雄: "精神分裂病と画像診断ー局所脳血流を中心にー" 精神医学. 32. 609-617 (1990)

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  • [Publications] 寺崎 太洋,大久保 善郎,松浦 雅人,小島 卓也: "精神分裂病患者脳波の定量的研究ー局所定常自己回帰モデルを用いた定常性の検討ー" 精神薬療基金研究年報. 21. 264-269 (1990)

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  • [Publications] 丹羽 信一: "分裂病の病態理解への精神生理学的接近" 精神医学. 32. 591-596 (1990)

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  • [Publications] 山口 成良,越野 好文: "誘発電位の基礎と臨床" 創造出版,東京, 1-68 (1990)

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  • [Publications] 地引 逸亀,山口 成良: "てんかん学の進歩NO.2ー1991" 岩崎学術出版社,東京, 181-197 (1991)

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  • [Publications] Niwa, S.: "Psychophysiological understanding of assumed neuronal basis of schizophrenia : Expectation for future possibilities." Seishin Igaku (Clinical Psychiatry). 32(6). 591-596 (1990)

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  • [Publications] Fukuda, M., Niwa, s. -I., et al.: "Psychological intervention can partly alter P300-amplitude abnormalities in schizophrenics." Jpn J Psychiatr Neurol. 43(4). 633-638 (1989)

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  • [Publications] Fukuda, M., Niwa, s. -I., et al.: "Psychological manipulation of P300 amplitude abnormalities in schizophrenics : Reconfirmation and extension of our previous result." ANN. Bull. RILP. 24. 243-256 (1990)

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  • [Publications] Kurachi, M., et al.: "Schizophrenia and brain imaging." Seishin Igaku (Clinical Psychiatry). 32(6). 609-617 (1990)

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  • [Publications] Kurachi, M.: "Biopsychological regions hitherto called endogenous." Japanese Journal of Psychopathology. 11(3). 197-204 (1990)

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  • [Publications] Yuasa, S., Kadono, Y., Tsunoda, M., Matsui, M., Emori, K., Minabe, Y., Fujii, T., and Kurachi, M.: "SPECT finding in schizophrenia : clinical correlates and the effect of neuroleptic treatment." Japanese Journal of Clinical Psychiatry. 19(12). 1840-1848 (1990)

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  • [Publications] Terasaki, O., Okubo, Y., Matsuura, M., and Kojima, T.: "A quantitative study on stationarity of EEGs of schizophrenics using locally stationary autoregressive model." Annual Report of the Pharmacopsychiatry Research Foundation. 21. 264-269 (1990)

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  • [Publications] Torii, H. and Kitamoto, F.: "Neuropsychological features of dementia of the Alzheimer type, with special reference to dysphasia." Proceedings of the Annual Meeting of the Japanese Research Group on Senile Dementia. 3. 21-26 (1989)

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  • [Publications] Jibiki, I. and Yamaguchi, N.: "Investigation of auditory brainstem responses and visual evoked potentials to pattern reversal stimulations in medicated schizophrenic patients." Jpn J EEG EMG. 18(4). 387-393 (1990)

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Published: 1993-03-16  

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