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1993 Fiscal Year Final Research Report Summary

A Study on the pathogenesis and mechanism of occurence of geriatric fractures.

Research Project

Project/Area Number 03454364
Research Category

Grant-in-Aid for General Scientific Research (B)

Allocation TypeSingle-year Grants
Research Field Orthopaedic surgery
Research InstitutionTottori University

Principal Investigator

YAMAMOTO Kichizo  Faculty of Med., Tottori University Prof., 医学部, 教授 (00032326)

Co-Investigator(Kenkyū-buntansha) HAGINO Hiroshi  Faculty of Med., Tottori University lecturer, 医学部・附属病院, 講師 (80208412)
KISHIMOTO Hideaki  Faculty of Med., Tottori University lecturer, 医学部, 講師 (00177817)
TESHIMA Ryota  Faculty of Med., Tottori University Associ.Prof., 医学部, 助教授 (50144671)
Project Period (FY) 1991 – 1993
Keywordsosteoporosis / femoral neck fracture / Histomorphometry / Non-invasive bone mineral measurement / scanning electron microscopy
Research Abstract

The result of this project consists of three part.
1) Non-invasive bone mineral measurements
The results of bone mineral measurements the spine by DXA was published in the title of "measurements of bone mineral density of lumbar vertebrae in the lateral projection by dual-energy X-ray absorptiometry-comparison with anteroposterior spinal and radial bone mineral measurements-" in J.Jpn. Orthop.Assoc., vol.67 : 49-57,1993. And the results of bone mineral measurements of os calcis was published in the J.Jpn.Orthop.Associ.vol.68 : 1044-1055,1994. under the title of "Bone mineral measurement of the calcaneus by single X-ray absoptiometry" The fracture threshold, defined as the 90% for calcaneus BMC in a women with a vertebral fracture was 313mg/cm^2 and 70.2% of the peak bone mass in the calcaneus.
2) Scanning electron microscopic study of iliac bone biopsy
The functional state of iliac cancellous bone in the postmenopausal women was investigated by SEM and revealed high resorbing activity in the early stage of postmenopause, which was published in Acta Anat. Nipponica vol.68 : 305-315,1993.
3) Histomorphometric Analysis of femoral neck specimen and iliac bone biopsy
To evaluate the bone mass and quality of the femoral neck spcimen and the histomorphometric analysis was performed, which exhibited an increased resorption cavity and intracortical porosity in the cortex as well as endocortical envelop. The bone volume in the femoral neck also significantly lower. However parameters of the iliac bone were not correlated with those of the femoral neck.

  • Research Products

    (4 results)

All Other

All Publications (4 results)

  • [Publications] 片桐浩史: "単一エネルギーX線吸収法による踵骨の骨量動態に関する研究" 日本整形外科学会雑誌. 68. 1044-1055 (1994)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 西原彰彦: "大腿骨頚部間側骨折患者の骨組織形態計測" 日本整形外科学会雑誌. 69(未定). (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] H.Katagiri: "Bone Mineral Measurement of the Calcaneus by Single X-ray Absorptiometry" Nippon Seikei-Geka Gakkai Zasshi. 68. 1044-1055 (1994)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] A.Nishihara: "Femoral Neck and Iliac Bone Histomorphometry in Femoral Neck Fracture" Nippon Seikei-Geka Gakkai Zasshi. 69 (in press).

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-03-09  

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