1995 Fiscal Year Final Research Report Summary
A study of preventive medicine on the individual variations in physico-endocrinological responses to stress
| Project/Area Number |
05454234
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| Research Category |
Grant-in-Aid for General Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Public health/Health science
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| Research Institution | National Institute for Environmental Studies |
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Principal Investigator |
KABUTO Michinori National Institute for Environmental Studies, Project Chief, 地域環境研究グループ, 総合研究官 (00113481)
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| Co-Investigator(Kenkyū-buntansha) |
IMAI Hideki National Institute for Environmental Studies, Researcher, 地域環境研究グループ, 研究員 (00232596)
KAGEYAMA Takayuki National Institute for Environmental Studies, Senior Researcher, 地域環境研究グループ, 主任研究員 (90204346)
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| Project Period (FY) |
1993 – 1995
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| Keywords | stress / physiology / endocrinology / CV-RR / CV-RR |
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| Research Abstract |
The RSA (respiratory sinus arrythmia), related to cardiac parasympathetic activity (PA), and MWSA (Mayr Wave sinus arrythmia), related to sympathetic activity (SA), components derived from spectral analysis of cardiac R-R intervals at rest were examined first for their relations with age, diet and obesity, which were found to be significant modulators, whereas stress-related personality and various stressors were not related. In the study on patients with panic disorders, the mean MWSA/RSA ratio as a more specific indication of SA was in the order of panic disorder>generalized anxiety disorder>controls, suggesting the feasibility of the methods as well as the hyperexcitation of the SA in the disorder as has been pointed out. An examination on the office workers revealed, moreover, MWSA/RSA ratio at awakeing rest correlated significantly with overworking time as well as commuting time. Finally, we clarified the correlation with sleep stage and the MWSA/RSA ratio showing the lowest value at deep sleep stage with a suggestion that the difference in the MWSA/RSA ratio between awaking rest and deep sleep may reflect mental stress at awaking rest as a new index.
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