1995 Fiscal Year Final Research Report Summary
Phase modulatim spectroscopy and brain imaging
| Project/Area Number |
06558115
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| Research Category |
Grant-in-Aid for Developmental Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Research Field |
Biomedical engineering/Biological material science
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| Research Institution | HOKKAIDO UNIVERSITY |
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Principal Investigator |
TAMURA Mamoru Hokkaido Univ. Research. Inst. Professor, 電子科学研究所, 教授 (80089888)
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| Project Period (FY) |
1994 – 1995
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| Keywords | Diffusing-Wave / Transport equation / Optical imaging / Human brain / Near-intrured light |
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| Research Abstract |
Diffusing-wave spectroscopy is the extension of dynamic light scattering from single-scattering to a multiple-scattering system and has attracted much interest as a mean of describing the behavior of photons in turbid media. In highly turbid media, the behavior of scattered photons can be described by a transport equation, which is usually reduced to a diffusion equation by diffusion approximation. Frequency-domain measurement of phase modulation method is the Fourier transform of the time-domain method, giving the information about the optical path.
In this study, we used the phase-modulation technique to describe the diffusing photons in turbid media, where absorption was changed. The diffusion constant, scattering and absorption constants were obtained in the phantom models. The application of diffusing-wave spectroscopy to human brain was proposed.
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