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1996 Fiscal Year Final Research Report Summary

Molecular cloning of the genes related with long term potentiation

Research Project

Project/Area Number 06640890
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field 動物生理・代謝
Research InstitutionOkazaki National Research Institutes

Principal Investigator

MARUYAMA Kei  Okazaki National Research Institutes National Institute for Physiological Sciences Associate Professor, 生理学研究所, 教授 (30211577)

Project Period (FY) 1994 – 1996
Keywordshelix-loop-helix / NeuroD / hippocampus / neuron / subtraction
Research Abstract

In the mammalian nervous system, several basic helix-loop-helix (bHLH) proteins have been identified that may play essential roles in neurogenesis or neural development. This paper describes a novel bHLH protein in rat brain, which has a bHLH domain highly homologous with that of MATH-2and NeuroD.On the other hand, the amino-acid sequence of the other regions had little homology with those of the known proteins. This protein consists of 381 amino acids and was detected only in neural tissue, indicating that it has an important role specific to neuronal activities.

  • Research Products

    (2 results)

All Other

All Publications (2 results)

  • [Publications] Maruyuama,Kei et al.: "Molecular cloning of a novel basic helics-loop-helics protein from the rat brain" Biochem.Biophys.Res.Commun.219. 526-530 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Maruyuama, Kei et al.: "Molecular cloning of a novel basic helics-loop-helics protein from the rat brain" Biochem.Biophys.Res.Commun.219. 526-530 (1996)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-03-09  

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