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1997 Fiscal Year Final Research Report Summary

Development of microangiography using synchrotron/radiation and high-definition video camera

Research Project

Project/Area Number 07557060
Research Category

Grant-in-Aid for Scientific Research (A)

Allocation TypeSingle-year Grants
Section展開研究
Research Field Circulatory organs internal medicine
Research InstitutionTokai University School of Medicine

Principal Investigator

MORI Hidezo  Tokai University School of Medicine Associate professor, 医学部, 助教授 (90146598)

Co-Investigator(Kenkyū-buntansha) TANIOKA Kenkichi  Nippon Hoso Kyokai (NHK) Chief Researcher, 主任研究員
HYODO Kazuyuki  National Lab.for High Energy Physics Instructor, 助手 (60201729)
ANDO Masami  National Lab.for High Energy Physic Professor, 教授 (30013501)
TANAKA Yutaka  Tokai University School of Medicine Assistant professor, 医学部, 講師 (50155181)
TANAKA Etsuro  Tokai University School of Medicine Assistant professor, 医学部, 講師 (80211366)
Project Period (FY) 1995 – 1997
KeywordsSynchrotron radiation / Angiography / High-definition video camera / microcirculation / circulatory disturbance / cancer
Research Abstract

We improved the originally reported synchrotron radiation (SR) micro-angiographic system by applying avalanche-type high-definition (HD) video camera. The New Super Harp HDTV (NHK,Tokyo) with high contrast resolution and effective quantum ratio of 640 allowed precise assessment of configuration of small vesseles (less than 100mum after digital processing) in heart, brain, and the other organs. The originally used image-intensifier-video camera system could not delineate small vessels well. Conventional HD video system using CCD could not reveal small vessels of heart and brain in situ. This system would allow us clinical evaluation of small vessel diseases in heart, brain, and the other organs and also visualization of newly developed small vessels due to angiogenesis in malignant tumor and circulatory disorders.

  • Research Products

    (26 results)

All Other

All Publications (26 results)

  • [Publications] Mori, H.et.al.: "Local continuity of myocardial blood flow studied by SR-excited XF spectrometry" Circulation Research. 76. 1088-1100 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 盛 英三, 他: "単色放射光を線源とする微小血管造影法とその臨床応用" 放射光. 8. 398-405 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Minamino, T.et.al.: "Bidirectional effects of aminophyline on myocardial ischemia" Circulation. 92. 1254-1260 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kitakaze, M.et.al.: "Role of Nitric oxide in regulation of coronary blood flow during myocarodial ischemia" JACC. 27. 1804-1812 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 盛 英三, 他: "放射光による微小血管撮影の原理とその応用" 診断と治療. 84. 164-169 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hori, H.et.al.: "Small vessel radiography in siyu with monochromatic synchrotron radiation" Radiology. 201. 173-177 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takeshita, S.et.al.: "Microanglographic assessment of collayeral vessol formation following direct gene transfer of VEGF" Cardiovascular Research. 35. 547-552 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takeshita, S.et.al.: "Use of SR microangiography to assess development of small collateral arteries in a rat model" Circulation. 95. 805-808 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 盛 英三, 他: "微小血管撮影" BME. 11. 29-36 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Tanaka, E.et.al.: "Coronary vasoconstrictive effects of NPY and their modulation by the A TP-sensitive K channel" JACC. 29. 1380-1389 (1977)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kitakaze, M.et.al.: "Temporary acidosis during reperfusion limits myocardial infarct size in dogs" Am J of Physiology. 272. H2071-H2078 (1977)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Node, K.et.al.: "Role of intracellular Ca^<2+> in a ctivation of prote in kinase c during ischemic" Circulation. 96. 1257-1265 (1977)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Y.Tanaka, H.Mori.et.al.: "Haga 97' proceedings" Springer Verlag (in press),

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mori H,et al.: "Local continuity of myocardial blood flow studied by SR-excited XF spectrometry." Circulation Research. 76. 1088-1100 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mori H,et al.: "Microangiography using monochromatic synchrotron radiation and its clinical application." Synchrotron Radiation. 8. 398-405 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Minamino T,et al.: "Bidirectional effects of aminophyline on myocardial ischemia" Circulation. 92. 1254-1260 (1995)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kitakaze M,et al.: "Role of nitric oxide in regulation of coronary blod flow during myocardial ischemia." JACC. 27. 1804-1812 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mori H,et al.: "Principles of microangiography using monochromatic synchrotron radiation and tis clinical application." Diagnosis and Therapy. 84. 164-169 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mori H,et al.: "Small vessel radioagraphy in situ with monochromatic synchrotron radiation." Radiology. 201. 173-177 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Takeshita S,et al.: "Microangiographic assessment of collateral vessel formation following direct gene transfer of VEGF." Caridovascular Researech. 35. 547-552 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Takeshita S,et al.: "Use of SR microangiography to assess development of small collateral arteries in a rat model." Circulation. 95. 805-808 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mori H,et al.: "Microangiography." BME. 11. 29-36 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tanaka E.et al.: "Coronary vasoconstrictive effects of NPY and their modulation by the ATP-sensitive K channel." JACC. 29. 1380-1389 (1977)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kitakaze M,et al.: "Temporary acidosis durintg rerperfusion limits myocardial infarct size in dogs." Am J Physiology. 272. H2071-H2078 (1977)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Node K,et al.: "Role of intracellular Ca2+ in activatiojn of protein kinase c during ischemia." Circulation. 96. 1257-1265 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tanaka Y,et al.: Haga 97 Proceedings. Springer Verlag (in press.),

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 1999-03-16  

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