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1997 Fiscal Year Final Research Report Summary

Splanchnic perfusion following open-heart surgery

Research Project

Project/Area Number 07671451
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionGunma University

Principal Investigator

ISHIKAWA Susumu  The second department of surgery, Gunma university school of medicine The associate professor, 医学部, 講師 (90241877)

Co-Investigator(Kenkyū-buntansha) OHTAKI Akio  The second department of surgery, Gunma university school of medicine The resear, 医学部, 助手 (80241876)
MORISHITA Yasuo  The second department of surgery, Gunma university school of medicine The chairm, 医学部, 教授 (40145470)
Project Period (FY) 1995 – 1997
KeywordsSplanchnic perfusion / Open-heart surgery / Cardiopulmonary bypass / Gastric intramucosal pH / Hepatic venous oxygen saturation
Research Abstract

To determine splanchnic perfusion after cardiopulmonary bypass, gastric intramucosal pH (pHi) and hepatic venous oxygen saturation (S_<HV>O_2) were measured in patients following open-heart surgery. Blood samples were analyzed at 6,12 and 24 hours after the admission to an intensive care unit (ICU). The results were as follows : 1)Gastric pHi increased significantly (p<0.01) from 7.21 at 6 hours to 7.31 at 12 hours and recovered to 7.37 at 24 hours, 2)S_<HV>O_2 increased significantly (p<0.05) from 48% at 6 hours to 57% at 12 hours and 24 hours, and 3)cardiac index was more than 4 L/min/m^2 and mixed venous oxygen saturation was over 70%. Despite sufficient cardiac output, splanchnic perfusion decreased after cardiopulmonary bypass and it recovered within 24 hours afrer admission to an ICU.In conclusion, gastric pHi and S_<HV>O_2 are useful parameters for postoperative splanchnic perfusion in patients with open-heart surgery.

  • Research Products

    (8 results)

All Other

All Publications (8 results)

  • [Publications] Ishikawa, S et al: "Noninvasive nasal mask BiPAP management for pnolonged respiratory failure following cardiovascular surgery." J Card Surg. 12. 176-179 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ishikawa, S et al: "Percutaneous transhepatic gallbladder.drainage for acute acalculous cholecystitis following cardiovascular Surgery." J,Cardiovasc Surg. 38. 513-515 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ishikawa, S et al: "Three-channeled aortic dissection" Ann Thorac Surg. 60・12. 1816-1818 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ishikawa, S et al: "Non-infective fever after replacement of thoracic aorta using collagen impregnated Dacnon prosthesis." J Cardiovasc Surg. 36. 143-145 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ishikawa, S et al: "Intrafracheul steut intubation under extracorporeal lung assist" Surg Today. 25. 995-997 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ishikawa, S et al: "Surgical management of enphysenatous giart bullae accompanied by severe broachial asthma:Report of a case." Surg Today. 25. 560-562 (1995)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 石川 進、森下 靖雄: "副作用症例データベース-診断と治療(増刊)" 診断と治療社, 1 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] 森下 靖雄, 石川 進: "虚血性心疾患(カレント内科(5))" 金原出版, 4 (1996)

    • Description
      「研究成果報告書概要(和文)」より

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Published: 1999-03-16  

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