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2000 Fiscal Year Final Research Report Summary

System Analysis for Higher Brain Function

Research Project

Project/Area Number 08279101
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Research InstitutionTohoku University

Principal Investigator

TANJI Jun  Tohoku Univ.Sch.Med.Dept.Physiol., Professor, 大学院・医学系研究科, 教授 (10001885)

Project Period (FY) 1996 – 1999
KeywordsBrain function / System analysis / experimental neuroscience / computational approach / imaging / cognition / motor behavior / memory
Research Abstract

To understand higher function of the brain, we have organized a group of researchers belonging to three broad categories : neuroscientists working on brain function of living animals experimentally, computational neuroscientists, and neuroscientists working on human subjects with noninvasive brain imaging techniques. Researchers of these multidisciplinary fields have worked not only individually in each fields of their own, but also have worked together to reach understanding of brain function from different aspects. Most importantly, with intensive workshops and seminars, cooperative works by researchers of different discipline have also been advanced.
New findings of interest have already evolved as the outcome of this research project. They include (1) understanding of cerebral cortical mechanisms for organizing sequencing of multiple movements, (2) visualization of functional organization in the primate inferetemporal cortex by the optical imaging technique, (3) discoverv of parietal neurons related to memory-guidance of hand movements, (4) visualization of enthorhinal-hippocampal interactions revealed by real-time imaging, and (5) discovery of neuronal activity in prefrontal cortex coding reward expectancy, among others. They have been published in major international scientific journals.

  • Research Products

    (14 results)

All Other

All Publications (14 results)

  • [Publications] Wang,G., Tanaka,K. and Tanifuji,T : "Optical imaging of functional in the monkey inferotemporal cortex."Science. 272. 1665-1668 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Gomi,H. and Kawato,M.: "Equilibrium-point control hypothesis examined by measured arm-stiffness during multi-joint movement"Science. 272. 117-120 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] lijima,T., et al.: "Entorhinal-hippocampal interactions revealed by real-time imaging."Science. 272. 1069-1232 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Watanabe,M.: "Reward expectancy in primate prefrontal neurons."Nature. 382. 629-632 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shima K, and Tanji,J.: "Role for cingulate motor area cells in voluntary movement selection based on reward."Science. 282. 1335-1338 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kitazawa S, Kimura T and Yin P-B.: "Cerebellar complex spikes encode both destinations and errors in arm movements."Nature. 392. 494-497 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Imamizu H. Miyauchi S. Tamada T. Sasaki Y. Takino R. Puetz B. Yohioka T. & Kawato M.: "Human cerebellar activity reflecting an acquired internal model of a new tool."Nature. 403. 192-195 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Wang, G., Tanaka, K.and Tanifuji, T.: "Optical imaging of functional in the monkey inferotemporal cortex."Science. 272. 1665-1668 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Gomi, H.and Kawato, M.: "Equilibrium-point control hypothesis examined by measured arm-stiffness during multi-joint movement."Science. 272. 117-120 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Iijima, T., et al.: "Entorhinal-hippocampal interactions revealed by real-time imaging."Science. 272. 1069-1232 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Watanabe, M.: "Reward expectancy in primate prefrontal neurons."Nature. 382. 629-632 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shima K, and Tanji, J.: "Role for cingulate motor area cells in voluntary movement selection based on reward."Science. 282. 1335-1338 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kitazawa S, Kimura T and Yin P-B.: "Cerebellar complex spikes encode both destinations and errors in arm movements."Nature. 392. 494-497 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Imamizu H.Miyauchi S.Tamada T.Sasaki Y.Takino R.Puetz B.Yohioka T.& Kawato M.: "Human cerebellar activity reflecting an acquired internal model of a new tool."Nature. 403. 192-195 (2000)

    • Description
      「研究成果報告書概要(欧文)」より

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Published: 2002-03-26  

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