• Search Research Projects
  • Search Researchers
  • How to Use
  1. Back to project page

2000 Fiscal Year Final Research Report Summary

Neural mechanisms for the selection of behavior and for the strategy of movement

Research Project

Project/Area Number 08279106
Research Category

Grant-in-Aid for Scientific Research on Priority Areas

Allocation TypeSingle-year Grants
Research InstitutionOsaka University

Principal Investigator

KIMURA Minoru  Osaka University, Faculty of Health and Sport Sciences, Professor, 健康体育部, 教授 (40118451)

Co-Investigator(Kenkyū-buntansha) KAWATO Mitsuo  ATR Human Information Processing Research Laboratories, Head, 室長
HIKOSAKA Okihide  Juntendo University, School of Medicine, Professor, 医学部, 教授 (70120300)
TANJI Jun  Tohoku University, Graduate School of Medicine, Professor, 大学院医学系研究科, 教授 (10001885)
MIZUNO Noboru  Kyoto University Graduate School of Medicine, Professor, 医学部, 教授 (10025596)
SHIBASAKI Hiroshi  Kyoto University Graduate School of Medicine, Professor, 医学部, 教授 (30037444)
Project Period (FY) 1996 – 1999
KeywordsProcedural learning / Basal ganglia / Supplementary motor area / Multiple paired forward-inverse models / Striatum / Nigrostriate dopamine system / Rod-bipolar synapse / Cerebellum
Research Abstract

Kimura et al. studied learning of sequential button press in the monkeys with unilateral dopamine depletion. They found that the monkeys had severe difficulty in learning motor strategy, if they used contralateral hand to the dopamine depletion. Their results clearly indicated that the basal ganglia are critically involved in learning behavioral strategy.
Tanji et al., studied single neuron activity in the dorsal and ventral premotor cortex (PMd, PMv) of monkeys which performed kinds of arm movements. They found that neuron activity of in the PMd and PMv represents kind of movement such as push, pull and turn of lever. This property makes sharp contrast to supplementary motor area.
Hikosaka et al., studied to identify brain areas which are involved in learning and memory of sequence motor acts. They found a line of evidence suggesting that preSMA is involved in learning associations between the stimulus and movement, and that the frontal cortices, the basal ganglia and the cerebellum play a crucial roles in learning and memory of sequence motor acts.
Kawato et al., demonstrated, on the bases of computational neurosciences, that "multiple paired forward-inverse models" which were proposed to be useful for learning sensory-motor integration are also useful for sensory-motor integration of human communications.
Mizuno et al., found new type of efferent neurons in the striatum which produce preprotachykinin and give rise to projections to the substantia innominata.
Kasai et al., studied properties of compensatory eye movements during strait head movements in human subjects.
Usui et al., analyzed synaptic transmission between ON type rod and bipolar cell in the retina and studied ionic mechanisms of ganglion cells.

  • Research Products

    (137 results)

All Other

All Publications (137 results)

  • [Publications] Kimura,M., Kato, M., et al: "Neural information transferred from the putamen to the globus pallidus during learned movement in the monkey."J.Neurophysiol. 76. 3771-3786 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Watanabe,K., and Kimura,M.: "Dopamine-receptor mediated mechanisms involved in the expression of learned activity of primate striatal neurons."J.Neurophysiol.. 79. 2568-2580 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Matsumoto,N., Hanakawa, T., et al.: "Role of nigrostriatal dopamine system in learning to perform sequential motor tasks in a predictive manner."J.Neurophysiol.. 82. 978-998 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hari R, Nagamine T, Nishitani N, Mikuni Ni, Sato T. Tarkiainen A, Shibasaki H: "Time-varying activation of different cytoarchiteconic areas of the human S1 cortex after tibial nerve stimulation."Neuroimage. 3. 195-201 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mima T, Terada K, Nagamine T, Ikeda A, Shibasaki H.: "Generator mechanisms of prprioception-related SEPs to passive joint movement of middle finger."Exp Brain Res. 111. 233-245 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nagahama Y, Fukuyama H, Yamauchi H, Matsuzaki S, Shibasaki H, Kimura J.: "Cerebral activation during performance of a card sorting test."Brain. 119. 1717-1721 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mikuni N, Nagamine T, Ikeda A, Terada K, Taki W, Kimura J, Kikuchi H, Shibasaki H.: "Simultaneous recording of epileptiform discharges by MEG and subdural electrodes in temporal lobe epilepsy."Neuroimage. 5. 298-306 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shibasaki,H. et al: "Activities of the primary and supplementary motor areas increase in preparation and execution of voluntary muscle relaxation : an event-related fMRI study."J Neurosci.. 19. 3527-3534 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ikeda,A., Yazawa,S., Kunieda,T., Ohara,S., Terada,K., Mikuni,N., Nagamine,T., Taki,W.: "Cognitive motor control in human pre-suplementary motor area studied by subdural recording of decrimunation/ selection-related cortical potentials."Brain. 122. 915-931 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shibasaki,H. et al: "Cognitive motor control in human pre-supplementary motor area studied by subdural recording of decrimunation/ selection-related cortical potentials."Brain. (in press). (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yazawa,S., Ikeda,A., Kunieda,T., Ohara,S., Mima,T., Nagamine,T., Taki,W., Hori,T., and Shibasaki,H.: "Human pre-supplementary motor area is active before voluntary movement : subdural recording of Bereitschaftspotentials from mesial frontal cortex."Exp Brain Res. (in press).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ohara,S., Ikeda,A., Kunieda,T., Yazawa,S., Baba,K., Nagamine,T., Taki,W., Hashimoto,N., Mihara,T., and : "Movement-related oscillatory change in human SMA proper."Brain. (in press).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shibasaki,H. et al: "Role of primary sensorimotor cortices in generating inhibitory motor response in humans."Brain. (in press).

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Ding,Y.-Q., Shigemoto,R.,Takada,M., Ohishi,H., Nakanishi,S. and Mizuno,N.: "Localization of the neuromedin K receptor (NK3) in the central nervous system of the rat."J.Comp.Neurol.. 364. 290-310 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yu-Qiang Ding, Takeshi Kaneko, Sakashi Nomura, and Noboru Mizuno.: "Immunohistochemical localization of μ-opiod receptors in the central nervous system of the rat."J.Comp.Neurol.. 367. 375-402 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takeshi Kaneko, Kazuhiko Saeki, Teffy Lee, and Noboru Mizuno.: "Improved retrograde axonal transport and subsequent visualization of tetramethyl- rhodamin (TMR) -dextran amine by means of an acid injection vehicle and antibodies against TMR."J.Neurosci.Methods. 65. 157-165 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Jin-laian-Li, Yu-Qiang Ding, Ryuichi Shigemoto. and Noboru Mizuno.: "Distribution of trigeminothalamic and spinothalamic tract-neurons showing P receptor-like immunoreactivity in the rat."Brain Res.. 719. 207-212 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sakashi Nomura, Yu-Qiang Ding, Takeshi Kaneko, Jin-Lian Li, and Noboru Mizuno.: "Localization of μ-opiod receptor-like immunoreactivity in the central components of the vagus nerve : A light and electron microscope study in the rat."Neuroscience. 73. 277-286 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] N Mizuno, S Nagata, and A Baba. et al: "Distribution of the mRNA for a pituitary adenylate cyclase-activating polypeptide receptor in the rat brain : An in situ hybridization study."J.Comp.Neurol.. 371. 567-577 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yun-Qing Li, Masahiko Takada, Takeshi Kaneko, and Noboru Mizuno.: "GABAergic and glycinergic neurons projecting to the trigeminal motor nucleus : A double labeling study in the rat."J Comp.Neurol.. 373. 498-510 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Akio Neki, Hitoshi Ohishi, Takeshi Kaneko, Ryuichi Shigemoto, Shigetada Nakanishi, & Noboru Mizuno.: "Metabotropic glutamate receptor GluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum."Neuroscience. 75. 815-826 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Jin-Lian Li, and Noboru Mizuno.: "Parabrachial neurons providing axons to both the thalamus and spinal cord in the rat."Brain Res. 745. 321-327 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Yun-Qing Li, Masahiko Takada, Takeshi Kaneko, and Noboru Mizuno.: "Distribution of GABA ergic and glycinergic premotor neurons projecting to the facial and hypoglossal nuclei in the rat."J Comp.Neurol.. 378. 283-294 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Jin-Lian Li, Takeshi Kaneko, Ryuichi Shigemoto, and Noboru Mizuno.: "Distribution of trigeminohypothalamic and spinohypothlamic tract neurons displaying substance Preceptor-like immunoreactivity in the rat."J Comp.Neurol. 378. 508-521 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Youichi Nishimura. Masahiko Takada. and Noboru Mizuno.: "Topographic distribution and collateral projections of the two major populations of nigro- thalamic neurons. A retrograde labeling study in the rat."Neurosci. Res. 28. 1-9 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] JunChen, Natsu Koyama, Takeshi Kaneko, and Noboru Mizuno.: "The locus coeruleus of the Japanese monkey (Macaca fuscata) does not express m-opioid receptor-like immunoreactivity."Brain Res. 755. 326-330 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] V.S.Seybold, I.Grkovic, A.L.Portbury, Y.-Q Ding, R Shigemoto, N,Mizuno,Furness, and B.R.Southwell.: "Relationship of NK3 receptor immuno- reactivity to subpopulations of neurons in rat spinal cord."J.Comp.Neurol.. 381. 439-448 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shobu Namura, Masahiko Takada, Haruhiko Kikuchi, and Noboru Mizuno.: "Collateral projecions of single neurons in the posterir thalamic region of both the temporal cortex and the amygdala : a fluorescent retrograde double-labeling study in the rat."J.Comp.Neurol.. 384. 59-70 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Jin- Lian Li, Takeshi Kaneko, Sakashi Nomura, Yun-Qing Li, and Noboru Mizuno.: "Association of serotonin-like immunoreactive axons with nociceptive projection neurons in the caudal spinal triqeminal nucleus of the rat."J.Comp.Neurol.. 384. 127-141 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Teffy Lee, Takeshi Kaneko, Kousuke Taki, and Noboru Mizuno.: "Prepro- dynorphin-, preproenkephalin-, and prepretachykinin-expressing neurons in the rat neostriatum : An analysis by immunocytochemistry and retrograde tracing."J.Comp.Neurol. (in press). (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Matsuzaka Y & Tanji J: "Changing directions of forthcoming arm movements : Neuronal activity in the presupplementary and supplementary motor area of monkey cerebral cortex."J.Neurophysiol.. 76. 2327-2342 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sakai ST, Inase M, Tanji J.: "Comparison of cerebellothalamic and pallidothalamic projections in the monkey (macaca fuscata) : a double anterograde labeling study."J.Comp.Neurol.. 368. 215-228 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Tanji J, Shima K.: "Supplementary motor cortex in organization of movement."Eur.Neurol.. 36. 13-19 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mushiake H, Fujii N, Tanji J.: "Visually guided saccade versus eye-hand reach : contrasting neuronal activity in the cortical supplementary and frontal eye fields."J.Neurophysiol.. 75. 2187-2191 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Inase M & Tanji J.: "Overlapping Corticostriatal Projections from the Supplementary Motor area and the Primary Motor Cortex in the Macaque Monkey : An Anterograde Double"J.Comp, Neurol.. 373. 283-296 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shima K, Hoshi E & Tanji J.: "Neuronal activity in the claustrum of the monkey during performance of multiple movements."J.Neurophysiol.. 75. 2115-2119 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Tanji J.: "New concepts of the supplementary motor area."Curr.Opin.Neurobiol. 6. 782-787 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mushiake H, Tanatsugu Y. & Tanji J.: "Neuronal activity in the ventral part premotor cortex during target-reach in modulated by direction of gaze."J.Neurophysiol.. 78. 567-571 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Inase M, Li B-M. & Tanji J.: "Dopaminergic modulation of neuronal activity inthe monkey putamen through D1 and D2 receptors during a delayed Go/Nogo task."Exp.Brain Res.. in press (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shima K, and Tanji, J.: "Role for cingulate motor area cells in voluntary movement selection based on reward."Science.. 282(5392). 1335-1338 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hoshi E., Shima K., and Tanji, J.: "Task-dependent selectivity of movement-related neuronal activity in the primate prefrontal cortex."J Neurophysiol.. 80(6). 3392-3397 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Shima K., and Tanji, J.: "Both supplementary and presupplementary motor areas are crucial for the temporal organization of multiple movements."J Neurophysiol.. 80(6). 3247-3260 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Tanji J and Fukuda H. et al.: "Oculomotor sequence learning : a positron emission tomography study."Exp Brain Res.. 122(1). 1-8 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Fujii N,, Mushiake, H. and Tanji, J.: "An oculomotor representation area within the ventral premotor cortex."Proc Nat Acad Sci USA.. 95(20). 12034-7 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Fujii N., Mushiake, H. and Tanji, J.: "Intracortical microstimulation of bilateral frontal eye field."J Neurophysiol.. 79(4). 2240-4 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Mushiake H, Fujii N, Tanji J: "Microstimulation of the lateral wall of the intraparietal sulcus compared with the frontal eye field during oculomotor tasks."J Neurophysiol.. 81(3). 1443-1448 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Fujii N., Mushiake, H. Tanji J: "Rostrocaudal distinction of the dorsal premotor area based on oculomotor involvement."J.Neurophyusiol.. 83 (13). 1764-1769 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Gomi,H. and Kawato,M.: "Equilibrium-point control hypothesis examined by measured arm-stiffness during multi-joint movement."Science. 272. 117-120 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Gomi,H. and Kawato,M.: "M. Human arm stiffness and equilibrium-point trajectory during multi-joint movement."Biological Cybernetics.. 76. 163-171 (1997)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Wolpert D, Kawato M: "Multiple paired forward and inverse models for motor control."Neural Networks. 11. 1317-1329 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kawato,M.: "Internal Models for motor control and trajectory planning."Current Opinion in Neurobiology. 9. 718-727 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Schweighofer-N ; Doya-K ; Kawato-M.: "Electropysiological properties of inferior olive neurons : A compartmental model."J-Neurophysiol.. 82(2). 804-17 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nakano-E ; Imamizu-H ; Osu-R ; Uno-Y ; Gomi-H ; Yoshioka-T ; Kawato-M.: "Quantitative examinations of internal representations for arm trajectory planning : minimum commanded torque change model."J-Neurophysiol.. 81(5). 2140-55 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] S Miyauchi, T Tamada, Y Sasaki, R Takino, B P, Toshinori Y, M Kawato: "Human cerebellar activity reflecting an acquired internal model of a new tool."Nature. 403(13). 192-195 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Hikosaka O, Sakai K, Miyauchi S, Takino R, Sasaki Y, Puetz B: "Activation of human presupplementary motor area in learning of sequential procedures : A functional MRI study."J Neurophysiol. 76. 617-621 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Miyashita K, Rand MK, Miyachi S, Hikosaka O: "Anticipatory saccadesin sequential procedural learning in monkeys."J Neurophysiol. 76. 1361-1366 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Miyashita N, Hikosaka O: "Minimal synaptic delay in the saccadic output pathway of the superior colliculus studied in awake monkey."Exp Brain Res. 112. 187-196 (1996)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sakai,K., Hikosaka,O., Miyauchi,S., Takino,R., Sasaki,Y., Puetz,B.: "Transition of brain activation from frontal to parietal areas in visuo-motor sequence learning."J.Neurosci.. 18. 1827-1840 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Lu,X., Hikosaka,O., Miyachi,S.: "Role of monkey cerebellar nuclei in skill for sequential movement."J.Neurophysiol.. 79. 2245-2254 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Takikawa,Y., Kawagoe, R., Miyashita,N.,Hikosaka,O.: "Presaccadic omnidirectional burst activity in the basal interstitial nucleus in the monkey cerebellum."Exp.Brain Res.. 121. 442-450 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nakamura,K., Sakai,K., Hikosaka,O.: "Neuronal activity in medial frontal cortex during learning of sequential procedures."J.Neurophysiol.. 80. 2671-2687 (1998)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Osu-R ; Gomi-H.: "Multijoint muscle regulation mechanisms examined by measured human arm stiffness and EMG signals."J-Neurophysiol.. 81(4). 1458-68 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nakamura K, Sakai K, Hikosaka O: "Effects of local inactivation of monkey medial frontal cortex in learning of sequential procedures."J Neurophysiol. 82. 1063-1068 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sakai K, Hikosaka O, Miyauchi S, Sasaki Y, Fujimaki N, Puetz B: "Pre-SMA activation during sequence learning reflects visuo-motor association."J Neurosci. 19. 1-6 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Sakai K, Hikosaka O, Miyauchi S, Takino R, Tamada T, Iwata NK, Nielsen M: "Neural representation of a rhythm depends on its interval ratio."J Neurosci. 19. 10074-10081 (1999)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Kimura, M., Kato, M., Shimazaki, H., Watanabe, K., and Matsumoto, N.: "Neural information transferred from the putamen to the globus pallidus during leamed movement in the monkey."J.Neurophysiol.. 76. 3771-3786 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Watanabe, K., and Kimura, M.: "Dopamine-receptor mediated mechanisms involved in the expression of learned activity of primate striatal neurons."J.Neurophysiol.. 79. 2568-2580 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Matsumoto, N., Hanakawa, T., Maki, S., Graybiel, A.M., and Kimura, M.: "Role of nigrostriatal dopamine system in learning to perform sequential motor tasks in a predictive manner."J.Neurophysiol.. 82. 978-998 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Matsumoto N., Hanakawa T., Maki S., Graybiel AM., Kimura M.: "Role ofnigrostriatal dopamine system in learning to perform sequential motor tasks in a predictive manner."J.Neurophysiol.. 82. 978-998 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hari R, Nagamine T, Nishitani N, Mikuni Ni, Sato T.Tarkiainen A, Shibasaki H: "Time-varying activation of different cytoarchiteconic areas of the human S1 cortex after tibial nerve stimulation."Neuroimage. 3. 195-201 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mima T, Terada K, Nagamine T, Ikeda A, Shibasaki H.: "Generator mechanisms of prprioception-related SEPs to passive joint movement of middle finger."Exp Brain Res. 111. 233-245 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nagahama Y, Fukuyama H, Yamauchi H, Matsuzaki S, Shibasaki H, & Kimura J.: "Cerebral activation during performance of a card sorting test."Brain. 119. 1717-1721 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mikuni N, Nagamine T, Ikeda A, Terada K, Taki W, Kimura J, Kikuchi H, Shibasaki H.: "Simultaneous recording of epileptiform discharges by MEG and subdural electrodes in temporal lobe epilepsy."Neuroimage. 5. 298-306 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Toma, K., Honda, M., Hanakawa, T., Okada, T., Fukuyama, H., Ikeda, A., Nishizawa, S., Konishi, J., and Shibasaki, H.: "Activities of the primary and supplementary motor areas increase in preparation and execution of voluntary muscle relaxation : an event-related fMRI study."J Neurosci.. 19. 3527-3534 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ikeda, A., Yazawa, S., Kunieda, T., Ohara, S., Terada, K., Mikuni, N., Nagamine, T., Taki, W., Kimura, J.and Shibasaki, H.: "Cognitive motor control in human pre-suplementary motor area studied by subdural recording of decrimunation/selection-related cortical potentials."Brain.. 122. 915-931 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ikeda, A., Yazawa, S., Kunieda, T., Ohara, S., Terada, K., Mikuni, N., Nagamine, T., Taki, W., Kimura, J.and Shibasaki, H.: "Cognitive motor control in human pre-supplementary motor area studied by subdural recording of decrimunation/selection-related cortical potentials."Brain.. (in press). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yazawa, S., Ikeda, A., Kunieda, T., Ohara, S., Mima, T., Nagamine, T., Taki, W., Hori, T., and Shibasaki, H.: "Human pre-supplementary motor area is active before voluntary movement : subdural recording of Bereitschaftspotentials from mesial frontal cortex."Exp Brain Res. (in press). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ohara, S., Ikeda, A., Kunieda, T., Yazawa, S., Baba, K., Nagamine, T., Taki, W., Hashimoto, N., Mihara, T., and Shibasaki, H.: "Movement-related oscillatory change in human SMA proper."Brain. (in press). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ikeda, A., Ohara, S., Matsumoto, R., Kunieda, T., Nagamine, T., Miyamoto, S., Kohara, N., Taki, W., Hashimoto, N., and Shibasaki, H.: "Role of primary sensorimotor cortices in generating inhibitory motor response in humans."Brain. (in press). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Usui, S., Ishihara, A., Kamiyama, Y.and Ishii, H.: "Ionic current model of bipolar cells in the lower vertebrate retina."Vision Research. 36. 4069-4076 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Usui, S., Kamiyama, Y., Ishii, H.and Ikeno, H.: "Reconstruction of retinal horizontal cell responses by the ionic current model."Vision Research. 36. 1711-1719 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Usui, S., Ishihara, A., Kamiyama, Y.and Ishii, H.: "Ionic current model of bipolar cells in the lower vertebrate retina."Vision Research. 36. 4069-4076 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kamiyama, Y., Ogura, T and Usui, S.: "Ionic current model of the vertebrate rod photoreceptor."Vision Research. 36. 4059-4068 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ishihara, A., Kamiyama, Y.and Usui, S.: "Analysis of light responses of the retinal bipolar cells based on inonic current model."Computational Neuroscience. 203-209 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Ding, Y.-Q., Shigemoto, R., Takada, M., Ohishi, H., Nakanishi, S.and Mizuno, N.: "Localization of the neuromedin K receptor (NK3) in the central nervous system of the rat."J.Comp.Neurol.. 364. 290-310 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yu-Qiang Ding, Takeshi Kaneko, Sakashi Nomura, and Noboru Mizuno.: "Immunohistochemical localization of μ-opiod receptors in the central nervous system of the rat."J.Comp.Neurol.. 367(3). 375-402 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Takeshi Kaneko, Kazuhiko Saeki, Teffy Lee, and Noboru Mizuno.: "Improved retrograde axonal transport and subsequent visualization of tetramethyl- rhodamine (TMR)-dextran amine by means of an acid injection vehicle and antibodies against TMR."J.Neurosci.Methods.. 65. 157-165 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Jin-Iaian-Li, Yu-Qiang Ding, Ryuichi Shigemoto, and Noboru Mizuno.: "Distribution of trigeminothalamic and spinothalamic tract-neurons showing P receptor-like immunoreactivity in the rat."Brain Res.. 719. 207-212 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sakashi Nomura, Yu-Qiang Ding, Takeshi Kaneko, Jin-Lian Li, and Noboru Mizuno.: "Localization of μ-opiod receptor-like immunoreactivity in the central components of the vagus nerve : A light and electron microscope study in the rat."Neuroscience. 73. 277-286 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hitoshi Hashimoto, Hiroyuki Nogi, Kensaku Mori, Hitoshi Ohishi, Ryuichi Shigemoto, Kyohei Yamamoto, Toshio Matsuda, Noboru Mizuno, Shigekazu Nagata, and Akemichi Baba.: "Distribution of the mRNA for a pituitary adenylate cyclase-activating polpeptide receptor in the rat brain : An in situ hybridization study."J.Comp.Neurol.. 371. 567-577 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yun-Qing Li, Masahiko Takada, Takeshi Kaneko, and Noboru Mizuno.: "GABAergic and glycinergic neurons projecting to the trigeminal motor nucleus : A double labeling study in the rat."J Comp.Neurol.. 373. 498-510 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Akio Neki, Hitoshi Ohishi, Takeshi Kaneko, Ryuichi Shigemoto, Shigetada Nakanishi, and Noboru Mizuno.: "Metabotropic glutamate receptor GluR2 and mGluR5 are expressed in two non-overlapping populations of Golgi cells in the rat cerebellum."Neuroscience. 75. 815-826 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Jin-Lian Li, and Noboru Mizuno.: "Parabrachial neurons providing axons to both the thalamus and spinal cord in the rat."Brain Res.. 745. 321-327 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Yun-Qing Li, Masahiko Takada, Takeshi Kaneko, and Noboru Mizuno.: "Distribution of GABA ergic and glycinergic premotor neurons projecting to the facial and hypoglossal nuclei in the rat."J Comp.Neurol.. 378. 283-294 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Jin-Lian Li, Takeshi Kaneko, Ryuichi Shigemoto, and Noboru Mizuno.: "Distribution of trigeminohypothalamic and spinohypothlamic tract neurons displaying substance P receptor-like immunoreactivity in the rat."J Comp.Neurol.. 378. 508-521 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Youichi Nishimura. Masahiko Takada. and Noboru Mizuno.: "Topographic distribution and collateral projections of the two major populations of nigro-thalamic neurons. A retrograde labeling study in the rat."Neurosci.Res.. 28. 1-9 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] JunChen, Natsu Koyama, Takeshi Kaneko, and Noboru Mizuno.: "The locus coeruleus of the Japanese monkey (Macaca fuscata) does not express m-opioid receptor-like immunoreactivity."Brain Res.. 755. 326-330 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] V.S.Seybold, I.Grkovic, A.L.Portbury, Y.-Q Ding, R Shigemoto, N.Mizuno, Furness, and B.R.Southwell.: "Relationship of NK3 receptor immuno- reactivity to subpopulations of neurons in rat spinal cord."J.Comp.Neurol.. 381. 439-448 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shobu Namura, Masahiko Takada, Haruhiko Kikuchi, and Noboru Mizuno.: "Collateral projecions of single neurons in the posterir thalamic region of both the temporal cortex and the amygdala : a fluorescent retrograde double-labeling study in the rat."J.Comp.Neurol.. 384. 59-70 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Jin- Lian Li, Takeshi Kaneko, Sakashi Nomura, Yun-Qing Li, and Noboru Mizuno.: "Association of serotonin-like immunoreactive axons with nociceptive projection neurons in the caudal spinal trigeminal nucleus of the rat."J.Comp.Neurol.. 384. 127-141 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Teffy Lee, Takeshi Kaneko, Kousuke Taki, and Noboru Mizuno.: "Prepro- dynorphin-, preproenkephalin-, and prepretachykinin-expressing neurons in the rat neostriatum : An analysis by immunocytochemistry and retrograde tracing."J.Comp.Neurol.. (in press). (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Matsuzaka Y & Tanji J.: "Changing directions of forthcoming arm movements : Neuronal activity in the presupplementary and supplementary motor area of monkey cerebral cortex."J.Neurophysiol. 76. 2327-2342 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sakai ST, Inase M, Tanji J.: "Comparison of cerebellothalamic and pallidothalamic projections in the monkey (macaca fuscata) : a double anterograde labeling study."J.Comp.Neurol.. 368. 215-228 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tanji J, Shima K.: "Supplementary motor cortex in organization of movement."Eur.Neurol.. 36. 13-19 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mushiake H, Fujii N, Tanji J.: "Visually guided saccade versus eye-hand reach : contrasting neuronal activity in the cortical supplementary and frontal eye fields."J.Neurophysiol.. 75. 2187-2191 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Inase M & Tanji J.: "Overlapping Corticostiatal Projections from the Supplementary Motor area and the Primary Motor Cortex in the Macaque Monkey : An Anterograde Double Labeling Study."J.Comp.Neurol.. 373. 283-296 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shima K, Hoshi E & Tanji J.: "Neuronal activity in the claustrum of the monkey during performance of multiple movements."J.Neurophysiol.. 75. 2115-2119 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Tanji J.: "New concepts of the supplementary motor area."Curr.Opin.Neurobiol. 6. 782-787 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mushiake H, Tanatsugu Y.& Tanji J.: "Neuronal activity in the ventral part premotor cortex during target-reach in modulated by direction of gaze."J.Neurophysiol.. 78. 567-571 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Inase M, Li B-M.& Tanji J.: "Dopaminergic modulation of neuronal activity inthe monkey putamen through D1 and D2 receptors during a delayed Go/Nogo task."Exp.Brain Res.. (in press). (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shima K, and Tanji, J.: "Role for cingulate motor area cells in voluntary movement selection based on reward."Science.. 282(5392). 1335-8 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hoshi E., Shima K., and Tanji, J.: "Task-dependent selectivity of movement-related neuronal activity in the primate prefrontal cortex."J Neurophysiol.. 80(6). 3392-7 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Shima K., and Tanji, J.: "Both supplementary and presupplementary motor areas are crucial for the temporal organization of multiple movements."J Neurophysiol.. 80(6). 3247-60 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kawashima R., Tanji J., Okada K., Suriura M., Sato K., Kinomura S., Inoue K., Ogawa A., and Fukuda H.: "Oculomotor sequence learning : a positron emission tomography study."Exp Brain Res.. 122(1). 1-8 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Fujii N., Mushiake, H.and Tanji, J.: "An oculomotor representation area within the ventral premotor cortex."Proc Natl Acad Sci USA.. 95(20). 12034-7 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Fujii N., Mushiake, H.and Tanji, J.: "Intracortical microstimulation of bilateral frontal eye field."J Neurophysiol.. 79(4). 2240-4 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Mushiake H, Fujii N, Tanji J: "Microstimulation of the lateral wall of the intraparietal sulcus compared with the frontal eye field during oculomotor tasks."J Neurophysiol. 81(3). 1443-1448 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Fujii N., Mushiake, H.Tanji J: "Rostrocaudal distinction of the dorsal premotor area based on oculomotor involvement."J.Neurophyusiol.. 83(3). (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Gomi, H.and Kawato, M.: "Equilibrium-point control hypothesis examined by measured arm-stiffness during multi-joint movement."Science. 272. 117-120 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Gomi, H.and Kawato, M.: "Human arm stiffness and equilibrium-point trajectory during multi-joint movement."Biological Cybernetics.. 76. 163-171 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Wolpert D, Kawato M: "Multiple paired forward and inverse models for motor control."Neural Networks. 11. 1317-1329 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Kawato, M.: "Internal models for motor control and trajectory planning."Current Opinion in Neurobiology. 9. 718-727 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Schweighofer-N ; Doya-K ; Kamato-M.: "Electrophysiological properties of inferior olive neurons : A compartmental model."J-Neurophysiol.. 82(2). 804-17 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakano-E ; Imamizu-H ; Osu-R ; Uno-Y ; Gomi-H ; Yoshioka-T ; Kawato-M.: "Quantitative examinations of internal representations for am trajectory planning : minimum commanded torque change model."J-Neurophysiol.. 81(5). 2140-55 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hiroshi Imamizu, Satou Miyauchi, Tomoe Tamada, Yuka Sasaki, Ryousuke Takino, Benno P, Toshinori Yoshioka, Mitsuo Kawato.: "Human cerebellar activity reflecting an acquired internal model of a new tool."Nature. 403(13). 192-195 (2000)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Hikosaka O, Sakai K, Miyauchi S, Takino R, Sasaki Y, Puetz B.: "Activation of human presupplementary motor area in learning of sequential procedures : A functional MRI study."J Neurophysiol. 76. 617-621 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Miyashita K, Rand MK, Miyachi S, Hikosako O.: "Anticipatory saccadesin sequential procedural learning in monkeys."J Neurophysiol. 76. 1361-1366 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Miyashita N, Hikosaka O.: "Minimal synaptic delay in the saccadic output pathway of the superior colliculus studied in awake monkey."Exp Brain Res. 112. 187-196 (1996)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Miyachi S, Hikosaka O, Miyashita K, Karadi Z, Rand Mk.: "Differential roles of monkey striatum in learning of sequential hand movement."Exp Brain Res. 1-5 (1997)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sakai, K., Hikosaka, O., Miyauchi, S., Takino, R., Sasaki, Y., Puetz, B.: "Transition of brain activation from frontal to parietal areas in visuo-motor sequence learning."J.Neurosci. 18. 1827-1840 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Lu, X., Hikosaka, O., Miyachi, S.: "Role of monkey cerebellar nuclei in skill for sequential movement."J.Neurophysiol.. 79. 2245-2254 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Takikawa, Y., Kawagoe, R., Miyashita, N., Hikosaka, O.: "Presaccadic omnidirectional burst activity in the basal interstitial nucleus in the monkey cerebellum."Exp.Brain Res.. 121. 442-450 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakamura, K., Sakai, K., Hikosaka, O.: "Neuronal activity in medial frontal cortex during learning of sequential procedures."J.Neurophysiol.. 80. 2671-2687 (1998)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Osu-R ; Gomi-H.: "Multijoint muscle regulation mechanisms examined by measured human arm stiffness and EMG signals."J-Neurophysiol.. 81(4). 1458-68 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Nakamura K, Sakai K, Hikosaka O.: "Effects of local inactivation of monkey medial frontal cortex in learning of sequential procedures."J Neurophysiol. 82. 1063-1068 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sakai K, Hikosaka O, Miyauchi S, Sasaki Y, Fujimaki N, Puetz B.: "Pre-SMA activation during sequence learning reflects visuo-motor association."J Neurosci. 19 : RC1. 1-6 (1999)

    • Description
      「研究成果報告書概要(欧文)」より
  • [Publications] Sakai K, Hikosaka O, Miyauchi S, Takino R, Tamada T, Iwata NK, Nielsen M.: "Neural representation of a rhythm depends on its interval ratio."J Neurosci. 19. 10074-10081 (1999)

    • Description
      「研究成果報告書概要(欧文)」より

URL: 

Published: 2002-03-26  

Information User Guide FAQ News Terms of Use Attribution of KAKENHI

Powered by NII kakenhi