1997 Fiscal Year Final Research Report Summary
Biomechanical Study on Reconstruced Mandible by Distraction Osteogenesis
| Project/Area Number |
08672298
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Surgical dentistry
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| Research Institution | Nagoya University (School of Medicne) |
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Principal Investigator |
SAWAKI Yoshihiro Nagoya University School of Medicine, Assistant Proffesor, 医学部, 講師 (00215906)
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| Co-Investigator(Kenkyū-buntansha) |
HAGINO Hiroko Nagoya University School of Medicine, Senior Resident, 医学部, 医員
ODA Tomoo Nagoya University School of Medicine, Senior Resident, 医学部, 医員
HATA Ken-ichiro Nagoya University School of Medicine, Assistant Proffesor, 医学部, 助手 (80293710)
KASUYA Masayo Nagoya University School of Medicine, Assistant Proffesor, 医学部, 助手 (20109325)
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| Project Period (FY) |
1996 – 1997
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| Keywords | distraction osteogenesis / mandibular reconstruction / osseointegrated implant / intraoral device / radiologic evaluation / histological observation |
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| Research Abstract |
This study was designed to evaluate the possibility of distraction osteogenesis in bridging segmental mandibular defectusing osseointegrated implants and an intraoral device. Ten adult dogs served as the subjects of this experiment. Their left mandibular premolars and first molar were extracted. Afetr 3 months for healing, three 10 mm x 3.75 mm osseointegrated implants were installed. Following 3 months for osseointegration, abutments and intraoral device which was originally made were connected to fixtuers. The mandible was resected and fixed with reconstruction plate. An osteotomy created a transport segment of 10 mm of the mandible. Each defect was vreated by cutting out a 15 mm. Wainting for a week as the latency period, distraction of transport segment was began at a rate of 1 mm/day. After distraction was completed, the distaction device was left for 8 weeks as the consolidation period. As the result, mandibular defecsts were filled with new formed bone. No mobility of the implants was observed during and after distraction. The gingiva which covered the defect was pushed out, and the gingiva over the regenerated bone were lengthened by distraction. Radiographic evaluation demonstrated new bone formation in the distraction gap and no bone resorption around the implants.
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