超伝導量子干渉装置を用いた味覚受容の研究

1999 Fiscal Year Final Research Report Summary

• Project/Area Number: 09671751
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Otorhinolaryngology
• Research Institution: KYUSHU UNIVERSITY
• Principal Investigator: YAMAMOTO Tomoya KYUSHU UNIVERSITY ASSOCIATE PROFESSOR, 医学部, 講師 (30230577)
• Co-Investigator(Kenkyū-buntansha): 山下 弘之 九州大学, 医学部, 助手 (10264029)
• Project Period (FY): 1997 – 2000
• Keywords: MEG / SQUID / taste / somatosensory / Operculm / human brain / magnetic evoked potential / Otolaryngology / magnetoencephalography

Research Abstract

Evoked magnetic response revealed that the somatosensory receptive field of oral, pharyngeal and laryngeal stimulation was located at the Operculm in the human brain. Taste receptive field was also localized in the Operclum close to the Insula region.
Resent progress in the magnetoencephalography (MEG) utilizing the super-conductive interference device (SQUID) made it possible to record the extremely weak magnetic signal emitted from the human brain. In the current paper, author developed the computer controlled device which stimulate the oral, pharyngeal and laryngeal mucosa by air-puff. This device also provided the taste solution to stimulate gustatory receptors in the tongue.

Research Products

• [Publications] Morioka T, Nishio S, Ishibashi H, Muraishi H, Muraishi M, Hisada K, Shigeto H, Yamamoto T, Fukui: "M: Intrisic epileptogenicity of focal cortical dysplasia as revealed by magneto-encephalography and electrocorticography."Epilepsy Reserch. 33. 177-187 (1999)
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• [Publications] Yamashita H, Kymamoto Y, Nakashima Y, Yamamoto Y, Inokuchi A, Komiyama: "S: Magnetic sensory cortical responses evoked by tactile stimulations of the human face, oral cavity and flap reconstrctions of the tongue"Eur Arch Otorhino-laryngol. 256. 42-46 (1999)
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• [Publications] Miyazaki H, Yamashita H, Masuda T, Yamamoto T, Komiyama: "S: Transcutaneous PPPCO2 monitoring in the evaluation of hyperventilation of patients with recurrent nerve paralysis"Eur Arch Otorhinolaryngol. 256. 47-50 (1999)
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• [Publications] Ikeda Y, Masuda T, Manako H, Yamashita H, Yamamoto T, Komiyama: "S : Quantitative evaluation of the voice range profile in patients with voice disorder."Eur Arch Otohinolaryngol. 256. 51-55 (1999)
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• [Publications] Kuratomi Y, Kumamoto Y, Yamashita H, Yamamoto T, Inokuchi A, Tomita K, Masuda A, Uehara S, Ohmagari J, Jingu K, Komiyama: "S: Comparison of survival rates of patients with nasopharyngeal carcinoma treated with radiotherapy, 5-fluorouracil and vitamin A("FAR" therapy)vs FAR therapy puls adjunctive cisplatin and pepleomycin chemotherapy"256. 60-63 (1999)
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• [Publications] Onitsuka T, Ninomiya H, Sato E, Yamamoto T, Tashiro: "N: The effect of interstimulus intervals and between-block rests on the auditory evoked potential and magnetic field : is the auditory p50 in humans an overlapping potential?"Clinical Neurophysiol. 110. 1-9 (1999)
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