1998 Fiscal Year Final Research Report Summary
The center of biological rhythm and neuroendocrine system
| Project/Area Number |
09680797
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Neuroscience in general
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| Research Institution | Kyoto Prefectural University of Medicine |
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Principal Investigator |
TAMADA Yoshitaka Dept.of Anatomy & Neuroboil., Kyoto Prefectural University of Medicine, Research Associate, 医学部, 助手 (60254364)
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| Co-Investigator(Kenkyū-buntansha) |
IIJIMA Norio Dept.of Anatomy & Neuroboil., Kyoto Prefectural University of Medicine, Research, 医学部, 助手 (00285248)
IBATA Yasuhiko Dept.of Anatomy & Neuroboil., Kyoto Prefectural University of Medicine, Professo, 医学部, 教授 (10079684)
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| Project Period (FY) |
1997 – 1998
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| Keywords | suprachiasmatic nucleus / ptotic stimulation / hypothalamus / circadian rhythm / astrocyte / optic nerve |
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| Research Abstract |
(1) Photic induction of NGFI-A gene expression was investigated in the SCN using in situ hybridization histochemistry. The broadness of NGFI-A mRNA and c-fos mRNA expression after photic stimulation were different. And NGFI-A gene induced in these cells of the SCN including VIP neurons are considered to be involved in circadian entrainment by light (Brain Res., 1997). (2) According to aging, the expression of VIP mRNA in the SCN was markedly decreased and their rhythm was disappeared (Neurosci.Lett., 1997). (3) The retinal projections to gastrin-releasing peptide (GRP) neurons in the SCN were investigated. The photic information is considered to be directly input from the optic nerve to GRP neurons and GRP neurons may be involved in circadian entrainment by light (NeuroReport 1997). (4) To explore the effect of photic stimulation in the astroglial elements in the hypothalamus, GFAP-like immunoreactive elements in the SCN and median eminence was investigated morphologically (Brain Res.Bull, 1998 ; Acta Histocem.Cytochem., 1998).
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[Publications] Kawakami, F., Okamura, H., Tamada, Y., Maebayashi, Y., Fukui, K.and Ibata, Y.: "Loss of day-night differences in VIPmRNA levels in the suprachiasmatic nucleus of aged rat" Neurosci.Lett.222. 99-102 (1997)
Description
「研究成果報告書概要(欧文)」より
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[Publications] Tanaka, M., Hayashi, S., Tamada, Y., Ikeda, T., Hisa, Y., Takamatsu, T.and Ibata, Y.: "Direct retinal projections to GRP neurons in the suprachiasmatic nucleus of the rat" NeuroReport. 8. 2187-2191 (1997)
Description
「研究成果報告書概要(欧文)」より
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[Publications] Tamada, Y.Tanaka, M., Munekawa, K., Hayashi, S., Okamura, H., Kubo, T., Hisa, Y.and Ibata, Y.: "Neuron-Glia Interaction in the Suprachiasmatic Nucleus : A Double Labeling Light and Electron Microscopic Immunocytochemical Study in the Rat" Brain Res., Bull. 45 (3). 281-287 (1998)
Description
「研究成果報告書概要(欧文)」より
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[Publications] Tamada, Y., Hayashi, S., Munekawa, K., Tanaka, M.Ikeda, T., Inoue, K.and Ibata, Y.: "Morphological Interactions between Glial Fibrillary Acidic Protein (GFAP)-like immunoreactive Elements and Lutenizing Hormone Relesing Hormone (LHRH)-like Immunoreactive Nerve Endings in the Median Eminence of the Rat-Double Labeling Immunoelectron Microscopic Study-." Acta Histochem.Cytochem.30 (5,6). 517-523 (1998)
Description
「研究成果報告書概要(欧文)」より
