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2000 Fiscal Year Final Research Report Summary

Time Series Analysis of Physical/Mental process in Human Brain

Research Project

Project/Area Number 10480052
Research Category

Grant-in-Aid for Scientific Research (B).

Allocation TypeSingle-year Grants
Section一般
Research Field Statistical science
Research InstitutionThe Institute of Statistical Mathematics

Principal Investigator

ISHIGURO Makio  The Institute of Statistical Mathematics, Dep. Prediction and Control, Professor, 予測制御研究系, 教授 (10000217)

Co-Investigator(Kenkyū-buntansha) OZAKI Tohru  The Institute of Statistical Mathematics, Dep. Prediction and Control, Professr, 予測制御研究系, 教授 (00000208)
NISHIMURA Chiaki  Department of Medical Informatics, Toho University School of Medicine, professor, 医学部, 教授 (50011193)
UCHIDA Sunao  Department of Psychophysiology, Tokyo Institute of Psyschatry, Principal Researcher, 副参事研究員 (00261181)
加藤 比呂子  NTTコミュニケーション科学基礎研究所, 知能情報研究部, 研究主任 (60284171)
SHIMODAIRA Hidetoshi  The Institute of Statistical Mathematics, Dep. Prediction and Control, Assistant professr, 予測制御研究系, 助手 (00290867)
TAKIZAWA Yumi  The Institute of Statistical Mathematics, Dep. Prediction and Control, Associate professr, 予測制御研究系, 助教授 (90280528)
Project Period (FY) 1998 – 2000
KeywordsGamma Band Oscillaltion / Multimodal Stimuli / Enllepsy EEG / Electric Fish Brain / Janken / Picture Analysis / Time Series Analysis / Experiment Paradigim
Research Abstract

This project started aiming at objective/statistical/time-series analysis of relation between mental and physical activity of human brain. Main results are with respect to EEG data. Analysis of th4e ECoG recorded form the medial and basal temporal cortices of human epileptic subjects revealed the presence of regular beta-1 oscillations of approximately 15 Hz (ranging from 10 to 20Hz).
W.R.T.MEG data : At perception level, the estimated locations of electric dipoles demonstrated good coincidence with those determined by invasive electrophysiological methods. At cognition level, significant activities in the dippocampus were found in the P300m time range. In an implicit motor imaging task, MEG revealed time course of ortical activities, something which had not benn possible in PET studies.
W.R.T.modelling : A nonlinear model, Interactive frequency Band Model, for the description of brain time-series data was developed ; and a program to produce 'Confidence Set of model' based on the estimate of variance of Infromation Criteria was developed.
Those results make a good foundation of future study of the Physical/Physiiological/Mental Process of the Brain.

  • Research Products

    (49 results)

All Other

All Publications (49 results)

  • [Publications] 内田直: "ヒトの大脳皮質ガンマ帯域オシレーション"脳の科学. 22・12. 1325-1331 (2000)

    • Description
      「研究成果報告書概要(和文)」より
  • [Publications] Nishimura,C. et al.: "Neuromagnetic Fields Elicited by a Bimodel Input"Proc.12th International Conference on Biomagnetism. (2001)

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      「研究成果報告書概要(和文)」より
  • [Publications] 西村千秋,熊谷徹,菊地吉晃: "異種感覚統合を含む脳内情報処理過程の脳磁気による検討"日本生体磁気学会誌. 13・1. 130-131 (2000)

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  • [Publications] 西村千秋 他: "異種感覚同時入力時の脳磁界反応"医用電子と生体工学. 38・特別号. 89 (2000)

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  • [Publications] Ozaki,T. et al.: "A comparison of non-linear non-parametric models for epilepsy data"Computers in Biology and Medicine. 31. 41-57 (2001)

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      「研究成果報告書概要(和文)」より
  • [Publications] Takizawa,Y. et al.: "Resolving Competing Theories for Control of the Jamming Avoidance Response : The Role of Amplitude Modulation in Electric Organ Discharge Decelerations"The Journal of Experimental Biology. 202. 1377-1386 (1999)

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  • [Publications] Rahman,Md.M.& Ishigura,M.: "Modelling Multivariate Trends of Non-Stationary Time Series for Estimating Dynamic Linear Relationship Among Them"Preprints of the Annual Meeting of Japan Statistical Society. 401-402 (2000)

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  • [Publications] 石黒真木夫,佐藤整尚: "じゃんけんプレーヤーモデルとデータ"日本統計学会報告集. 27-28 (2000)

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  • [Publications] 石黒真木夫,佐藤整尚: "2次元3値時系列としてのジャンケンデータの研究"Research Memorandum, The Institute of Statistical Mathematics. No.759. (2000)

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  • [Publications] Ishiguro,M. et al.: "Estimating Linear Relationships Among Multiple Trends of Nonstationary Time Series"Research Memorandum, The Institute of Statistical Mathematics. No.755. (2000)

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  • [Publications] Yafune, A.& Ishiguro, M.: "Kullback-Leibler Information Approach for Modifying Pharmacokinetic Sampling Schedules in Clinical Phase I Trials"Research Memorandum. No.679. (1998)

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  • [Publications] Ishiguro, M.: "Teleological Model (in Japanese)"Proceedings of the Institute of Statistical Mathematics. Vol.46 No.2. 383-399 (1998)

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  • [Publications] Ishiguro, M.: "Technical Aspects of Information Criterion Statistics (in Japanese)"Proceedings of the Institute of Statistical Mathematics. Vol.47, No.2. 395-424 (1999)

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  • [Publications] Ishiguro, M.: "Interactive Frequency Band Model, Research Memorandum No. 717"The Institute of Statistical Mathematics, Tokyo. (1999)

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  • [Publications] Ishiguro, M., Kato, H.and Akaike, H.: "Auto-Regressive model analyzer"Computer Science Monographs, ARdock. 30. (1999)

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  • [Publications] Yafune, A.and Ishiguro, M.: "Bootstrap Approach for Constructing Confidence Intervals for Population Pharmacokinetic Parameters (Part I)-A Use of Bootstrap Standard Error-"Statistics in Medicine. 18. 581-599 (1999)

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  • [Publications] Ishiguro, M.et al.: "Survival analysis after surgical operation for esophageal cancer based on EIC"Japanese Journal of Biometrics. 20, 1. 93-107 (1999)

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  • [Publications] Rahman, Md.M.& Ishiguro, M.: "Modelling Multivariate Trends of Non-Stationary Time Series for Estimating Dynamic Linear Relationship Among Them"Preprints of the Annual Meeting of Japan Statistical Society. 401-402 (2000)

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      「研究成果報告書概要(欧文)」より
  • [Publications] Ishiguro, M.and Sato, S.: "Study of Janken Data as Two-dimeinsional Tri-nomial Time Series, Research Memorandum No. 759 (in Japanese)"The Institute of Statistical Mathematics, Tokyo.. (2000)

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  • [Publications] Ishiguro, M.et al.: "Estimating Linear Relationships Among Multiple Trends of Nonstationary Time Series, Research Memorandum"The Institute of Statistical Mathematics. No.755. (2000)

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  • [Publications] Uchida S.et al.: "Benzodiazepine effects on human sleep EEG spectra : A comparison of triazolam and flunitrazepam"Life Sciences. Vol.63. 675-684 (1998)

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  • [Publications] N.Hirai, S.Uchida, T.Maehara, Y.Okubo and H.Shimizu.: "Enhanced gamma (30-150 Hz) frequency in the human medial temporal lobe"Neuroscience. Vol.90, No.4. 1149-1155 (1999)

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  • [Publications] Nobuhide Hirai, Sunao Uchida, Taketoshi Maehara, Yoshiro Okubo and Hiroyuki Shimizu: "Beta-1 (10-20 Hz) cortical oscillations observed in the human medial temporal lobe"NeuroReport. Vol.10, No.14. 3055-3059 (1999)

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  • [Publications] Uchida S.et al.: "Roles of midbrain and neocortex during human non-REM sleep assesed by PET"J.Neurosci. 19. 10065-10073 (1999)

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  • [Publications] Uchida S.et al.: "A comparison of period amplitude analysis and FFT power spectral analysis of all-night human sleep EEG"Physiol. Behav.. 67. 1. 121-131 (1999)

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  • [Publications] S.Uchida, H.Nadayama, T.Maehara, N.Arakaki, M.Nakamura, T.Naka, S.bayashi and H.Shimizu: "Suppression of gamma activity in the human medial temporal lobe by sevoflurane anesthesia"Neuroreport. No.11. 39-42 (2000)

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  • [Publications] Nishimura C, Kumagai T, Kikuchi Y and Endo H.: "Neuromagnetic Fields Elicited by Multimodel Inputs"Recent Advances in Biomagnetism Proceeding of the 11th International Conference on Blomagnetism. 700-703 (1998)

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  • [Publications] Nishimura, C.: "Studies of the Working Human Brain by Neuromagnetic Field Measuremlent (in Japanese)"Journal of the Medical Society of Toho University. 45 (2). 195-200 (1998)

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  • [Publications] C.Nishimura, T.Kumagai, Y.Kikuchi and H.Endo: "Neuromagnetic Fields Elicited by a Bimodel Input"12th International Conference on Biomagnetism, August 13-17. (2000)

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  • [Publications] Shoji, I.and Ozaki, T.: "Estimation for nonlinear stochastic differential equations by a local linearization method"Stochastic Analysis and Applications. 16. 733-752 (1998)

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  • [Publications] Shoji, I.and Ozaki, T.: "A statistical method of estimation and simulation for systems of stochastic differential equations"Biometrika. 85. 240-243 (1998)

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  • [Publications] T.Ozaki et al.: "Nonlinear Time Series Models and Neural Dynamical Systems"Research Memorandum. No.657. (1998)

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  • [Publications] Ozaki, T., P.A.Valdes-Sosa: "Reconstructing the Nonlinear Dynamics of Epilepsy Data Using Nonlinear Time Series Analysis"J.of Signal Processing. 3. 153-162 (1999)

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  • [Publications] Ozaki, T.et al.: "Empirical Evaluation of Non-parametric Autoregressive Models for Dynamics Reconstruction and Prediction"J.of Signal Processing. 3. (1999)

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  • [Publications] Valdes, P., Jimenez, J.C., Riera, J., Biscay, R.and Ozaki, T.: "Nonlinear EEG Analysis based on a neural Mass Model"Biological Cybernetics. 81. 415-424 (1999)

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  • [Publications] Jimenez, J.C., Shoji, J.and Ozaki, T.: "Simulation of stochastic differential equations through the local linearization method. A comparative study"J.of Statistical Physics. 94. 587-602 (1999)

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  • [Publications] Shi, Z., Tamura, Y.and Ozaki, T.: "Nonlinear time series modeling by radial basis function-based state-dependent autoregressive model"International Journal of Systems Science. 30. 717-727 (1999)

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  • [Publications] Ozaki, T., Jimenez, J.C.and Ozaki, V.H.: "Role of the Likelihood Function in the Estimation of Chaos Models"J.of Time Series Analysis. Vol.21. 363-387 (2000)

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  • [Publications] F.Miwakeichi, Ruben Ramirez-Padron, Pedro A.Valdes-Soda and T.Ozaki: "A comparison of non-linear non-parametric models for epilepsy data"Computers in Biology and Medicine. 31. 41-57 (2001)

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  • [Publications] Takizawa, Y.et al.: "Analysis of Brain Electroencephalograms with the Instantaneous Maximum Entropy Method"Signal Processing IX, Theories and Applications. Vol.II. 661-664 (1998)

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  • [Publications] Yumi Takizawa, Gray J.Rose, Masashi Kawasaki: "Resolving Competing Theories for Control of the Jamming Avoidance Response : The Role of Amplitude Modulations in Electric Organ Discharge Decelerations"The Journal of Experimental Biology. 202. 1377-1386 (1999)

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  • [Publications] Yumi Takizawa, Makio Ishiguro, Atsushi Fukasawa, Sumio Ohkawa: "Spectral Analysis of Nonstationary Signals on a Two Dimenesional Space"ISIE '99-Bled, Slovenia. (1999)

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  • [Publications] Shimodaira, H., Hasegawa, M.: "Multiple comparisons of log-likelihoods with applications to phylogenetic inference"Molecular Biology and Evolution. 16. 1114-1116 (1999)

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  • [Publications] Kato, H., Kawahara, H.& Ishiguro, M.: "On the Coefficient-Modulated Autoregressive Model"Technical Report. No.98-12. (1998)

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  • [Publications] Ishiguro, M.and Oya, T.: "Analysis of a Human/2-wheeled-Vehicle System by ARdock, in The Practice of Time seires Analysis"Springer-Verlag New York, Inc.. 209-228 (1999)

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  • [Publications] Ozaki, T., Jimenez, J.C., Biscay, R.and Valdes-Sosa, V.: "Nova Science Publishers, edited by N.Pradhan, P.E.Rapp & R.Sreenivasan"Nonlinear Time Series Models and Neural Dynamical Systems", in Nonlinear Dynamics & Brain Functioning. (1999)

    • Description
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  • [Publications] Valdes-Sosa, P., Bosch, , Jimenez, J.C., Trujillo, N., Biscay, R., Morales, F., Hernandez, J.L., Ozaki, T.: "Nova Science Publishers, edited by N.Pradhan, P.E.Rapp & R.Sreenivasan""The Statistical Identification of Nonlinear Brain Dynamics : A Progress Report", in "Nonlinear Dynamics & Brain Functioning". (1999)

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  • [Publications] Ozaki, T.Shi, Z.: "Aihara & Aizawa Ed., Saiennsu-Sha"ExpAR Models and Chaos, in Fromtier of Chaos Research. 101-111 (1999)

    • Description
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  • [Publications] Ozaki, T., P.Valdes-Sosa, V.Haggan-Ozaki and Shi, Z: "Edited by S.K.Malik, M.K.Chandrashekaran, and N.Pradhan, Indian National Science Academy, New Delhi"Prediction-based Characterization of Chaotic Phenomena in Bio-Sciences, in Nonlinear Ohenomena in Biological & Physical Sciences. 65-121 (2000)

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Published: 2002-03-26  

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