2000 Fiscal Year Final Research Report Summary
The mechanism of bio-motor by using single nano-manipulation
| Project/Area Number |
10558108
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| Research Category |
Grant-in-Aid for Scientific Research (B).
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
Biophysics
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| Research Institution | Department of Applied Physics, Graduate School of Engineering, NAGOYA University |
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Principal Investigator |
ISHIJIMA Akihiko Department of Applied Physics, Graduate School of Engineering, NAGOYA University, Associate Professor, 工学研究科, 助教授 (80301216)
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| Project Period (FY) |
1998 – 2000
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| Keywords | Optical tweezers / Nano-manipulation / Single molecule measurement / Chara myosin / ATP |
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| Research Abstract |
In Characean cells, the endoplasm streams along the actin cables are at 30-100 μm/s. This sliding velocity is about 5 times faster than no load shortening velocity of skeletal muscle(10 μm/s). However, the mechanism about this high sliding speed of the endoplasm streams haven' t been understood yet. We want to perform dynamic measurement on single molecular level of this Chara myosin to elucidate the molecular mechanism that can produce high sliding speed.
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