2001 Fiscal Year Final Research Report Summary
Development of Continuous Preparation Process of Functional Microspheres Using Continuous Reactor with Vibrating
| Project/Area Number |
11555202
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
化学工学一般
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| Research Institution | MIYAZAKI UNIVERSITY |
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Principal Investigator |
KAWANO Yoshinobu MIYAZAKI UNIVERSITY, ENGINEERING, PROFESSOR, 工学部, 教授 (10040974)
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| Co-Investigator(Kenkyū-buntansha) |
MURATA Hisashi MIYAZAKI UNIVERSITY, AGRICULTURE, PROFESSOR, 農学部, 教授 (60041018)
SUGIMITO Yasuhiro MIYAZAKI UNIVERSITY, AGRICULTURE, PROFESSOR, 農学部, 教授 (20041030)
HATATE Yasuo KAGOSH1MA UNIVERSITY, ENGINEERING, PROFESSOR, 工学部, 教授 (00038051)
TANIGUCHI Toru REIKA INDUSTRY CO., PRESIDENT, 社長(研究職)
SHIOMORI Koichiro MIYAZAKI UNIVERSITY, ENGINEERING, ASSOCIATE PROFESSOR, 工学部, 助教授 (80235506)
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| Project Period (FY) |
1999 – 2001
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| Keywords | Microcapsules / Boidegradable Polymer / Agricultural Chemicals / Solvent Evaporation Method / Controlled Release / Particle diameter / Continuous preparation apparatus |
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| Research Abstract |
Biodegradable microcapsules entrapping activated carbon impregnated with fenitrothion (MEP) which was used as a pesticide were prepared by the solvent evaporation method in a (solid/oil/water) complex emulsion system Biodegradable poly-caprolactone (PCL) was used as a wall material. Effects of preparation conditions (polymer concentration, surfactant concentration, hold-up of dispersed phase, MEP concentration, emulsion stabilizer, agitation speed) on the capsule morphology, entrapment efficiency and release profile of MEP were investigated. The microcapsules were able to be successfully prepared under the condition in which there were relatively large quantities of PCL and activated carbon for MEP. The release profile of MEP would be able to control by the preparation condition of the microcapsules. The effectiveness test for the plant of the microencapsulated pesticide (MEP), such as sustained-release performance and crop injury, was carried out. It was confirmed that the encapsulation was effective for the pesticide.
Furthermore, the continuous apparatus with vibration mixing plates for the production of microcapsules and microspheres was developed. The continuous preparation of microcapsules were carried out by the in-situ polymerization in the O/W emulsion system of styrene and divinylbenzene at various conditions. Then, the operation method by this process was examined and the operating condition was clarified. Furthermore, the continuous preparation procedure of the pesticide microcapsules which made biodegradable polymer was developed.
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