2001 Fiscal Year Final Research Report Summary
Development of a computor-controlled gustatory stimulator for magnetoencephalography
| Project/Area Number |
11557135
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
Functional basic dentistry
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| Research Institution | Osaka University |
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Principal Investigator |
YAMAMOTO Takashi Osaka Univ., Fac. Human Sci., Professor, 大学院・人間科学研究科, 教授 (60028793)
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| Co-Investigator(Kenkyū-buntansha) |
INUI Tadashi Osaka Univ., Fac. Human Sci., Res. Associate, 大学院・人間科学研究科, 助手 (40324735)
YAMAGUCHI Masahiko Life-elec lab., AIST, Director, 関西センター・ライフエレクトロニクス研究ラボ, 主任研究官
TONOIEKE Mitsuo Life-elec lab., AIST, Deputy Director, 関西センター・ライフエレクトロニクス研究ラボ, 副研究ラボ長
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| Project Period (FY) |
1999 – 2001
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| Keywords | taste / stimulator / electroencephalography |
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| Research Abstract |
The magnetoencephalography (MEG) is one of the non-invasive functional brain imaging techniques. MEG has good temporal resolution in comparison to functional magnetic resonance imaging (fMRI) or positron emission tomography (PET), and can give a good estimation of the localization of the activity much more precisely than electroencephalography. The purpose of the present study is to construct a convenient equipment controlled by a computer system to deliver taste solutions to the subject's tongue with accurate onset times.
A newly manufactured computer-controlled stimulus delivery system was constructed to apply taste solution and rinsing water through a Teflon tube to a flow chamber covering the anterior part of the subject's tongue. A small babble was inserted between the rinse and taste solution to prevent diffusion of fluids. The flow rate the water and stimuli was 200 ml/min. The outlet from the chamber was led to outside of the shielded room and the taste solutions and rinsing water were discarded. Taste solutions were colored red to allow their detection by an optical sensor, but water was not colored. The sensor was positioned just before the entry to the mouthpiece. This onset of taste stimulation provided a trigger signal for MEG averaging.
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Research Products
(22 results)
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[Publications] K. Kobayashi, Y. Noda, N. Matsushima, K. Nishi, H. Sawada, T. Nagatsu, D. Nakahara, R. Fukabori, Y. Yasoshima, T. Yamamoto, M. Miura, M. Kano, T. Mamiya, Y. Miyamoto and T. Nabeshima: "Modest neuropsychological deficits caused by reduced noradrenaline metabolism in mice heterozygous for a mutated tyrosine hidroxylase gene"Journal of Neuroscience. 20(6). 2418-2426 (2000)
Description
「研究成果報告書概要(欧文)」より
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