2000 Fiscal Year Final Research Report Summary
Alteration of exhaled NO by domestic Nox pollution
| Project/Area Number |
11671713
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
Otorhinolaryngology
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| Research Institution | KANSAI MEDICAL UNIVERSITY |
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Principal Investigator |
KUBO Nobuo Kansai Medical University, Faculty of Medicine, Assistant Professor, 医学部, 助教授 (70186435)
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| Co-Investigator(Kenkyū-buntansha) |
IKEDA Hiroki Kansai Medical University, Faculty of Medicine, assistant, 医学部, 助手 (90288803)
MINAMI Toyohiko Kansai Medical University, Faculty of Medicine, assistant, 医学部, 助手 (10239311)
NAKAMURA Akihiko Kansai Medical University, Faculty of Medicine, Lecturer, 医学部, 講師 (90180356)
YOSHINAGA Kazuhito Kansai Medical University, Faculty of Medicine, assistant, 医学部, 助手 (20309256)
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| Project Period (FY) |
1999 – 2000
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| Keywords | nitric oxide / nitric dioxide / indoor pollution / exhaled NO |
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| Research Abstract |
With or without running air conditioner, domestic concentrations of nitric oxide (NO) and nitrogen dioxide (NO_2) are monitored by rapid response chemiluminescence NO analyzers with NO_2 converter during gas cooking and smoking. In air-conditioned room, gas burning (5000 cal for 60 minutes) elevated NO and NO_2 concentrations up to 3.2 ppm and 0.8 ppm, respectively. In the air-conditioned room, tobacco smoking (36 cigarettes for 60 minutes) increased NO and NO_2 concentration up to 0.8 ppm and 1.1 ppm, respectively. In both conditions, NO_2 concentration exceeds the Japanese ambient air quality standard (0.06ppm) within 2 minutes after starting burning. Since NO_2 can be formed by the reaction of oxygen and NO, certain amount of NO should be changed to be the toxic compound of NO_2. Current results suggest that domestic concentration of NO_2 can potentiate the airway response to the residents during gas cooking and smoking.
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