2001 Fiscal Year Final Research Report Summary
Joint Research on Preparation of Novel Bioconjugates
| Project/Area Number |
11694114
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 一般 |
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| Research Field |
高分子構造・物性(含繊維)
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| Research Institution | HOKKAIDO UNIVERSITY |
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Principal Investigator |
NISHI Norio Hokkaido Univ., Graduate School of Environmental Earth Science, 大学院・地球環境科学研究科, 教授 (70001857)
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| Co-Investigator(Kenkyū-buntansha) |
KAKUCHI Toyoji Hokkaido Univ., Graduate School of Engineering, 大学院・工学研究科, 教授 (80113538)
SAKAIRI Nobuo Hokkaido Univ., Graduate School of Environmental Earth Science, 大学院・地球環境科学研究科, 教授 (60153863)
NISHIMURA Shin-ichiro Hokkaido Univ., Graduate School of Science, 大学院・理学研究科, 教授 (00183898)
NOMIZU Motoyoshi Hokkaido Univ., Graduate School of Environmental Earth Science, 大学院・地球環境科学研究科, 助教授 (00311522)
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| Project Period (FY) |
1999 – 2001
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| Keywords | Bioconjugate / protein / nucleic acid / polysaccharide / bio-related polymer / DNA-chitosan bilayer membrane / DNA-collagen bioconjugate / Insolubilized DNA |
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| Research Abstract |
Research on bio-related polymeric materials, such as nucleic acid(DNA and RNA), peptide, protein, polysaccharide, lipid, has developed extensively in resent years. However, the each research fields for these materials have their own world, and their mutual exchange and colaborations are not popular so far. Very fine functional materials would be found between their field or in their conjugated fields. We intended to prepare novel bioconjugate by the contact discussion and colaboration of Japanese and German researchers on various biorelated polymers.
As a result, following researches have been carried out.
1. Preparation of DNA-chitosan bilayer membrane for surgecal use.
2. Basic research on syntehsis of glycopeptide and glycoprotein.
3. Insolubilization of DNA by UV-irradiation.
4. Preparation of DNA-collagen bioconjugate.
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