2002 Fiscal Year Final Research Report Summary
Synthetic studies on the glycopeptides drugs
| Project/Area Number |
12555256
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| Research Category |
Grant-in-Aid for Scientific Research (B)
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| Allocation Type | Single-year Grants |
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| Section | 展開研究 |
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| Research Field |
Synthetic chemistry
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| Research Institution | Hokkaido University |
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Principal Investigator |
NISHIMURA Shin-ichiro Hokkaido Univ., Grad. School of Science., Prof., 大学院・理学研究科, 教授 (00183898)
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| Co-Investigator(Kenkyū-buntansha) |
MAEKAWA Yoshinobu Chemical Biology Institute, Inc. Chief Research Coordinator, 主席研究員
KONDO Hirosato Shionogi & Co., LTD General Manager, 部長
NISHIMURA Takashi Hokkaido Univ., Institute for Generic Medicine., Prof., 遺伝子病制御研究所, 教授 (30143001)
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| Project Period (FY) |
2000 – 2002
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| Keywords | glycopeptide / glycosyltransferase / cyclic glycopeptide / influenza virus / cell adhesion / antifreeze glycoprotein / 癌転移 / 糖転移酵素 |
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| Research Abstract |
Molecular design and syntheses of the novel type of glycopeptides were carried out in order to create therapentic reagents in cellular adhesion diseases such as cancer, viral infection, and inflammatory.
Efficient and versatile synthetic schemes were established by means of combined chemical and enzymatic procedures.
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