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2005 Fiscal Year Final Research Report Summary

Establishment of support technology for the development of surgical training simulator

Research Project

Project/Area Number 14370419
Research Category

Grant-in-Aid for Scientific Research (B)

Allocation TypeSingle-year Grants
Section一般
Research Field Thoracic surgery
Research InstitutionWaseda University

Principal Investigator

UMEZU Mitsuo  Waseda University, Faculty of Science and Engineering, Professor, 理工学術院, 教授 (90132927)

Co-Investigator(Kenkyū-buntansha) KAWAZOE Kouhei  Iwate Medical University, Professor, 第三外科, 教授 (50075561)
IWASAKI Kiyotaka  Waseda University, Consolidated Research Institute for Advanced Science and Medical Core, Lecturer, 生命医療工学研究所, 講師 (20339691)
Project Period (FY) 2002 – 2005
KeywordsArtificial organ technology / Living system / Cardiovascular disease / Mock circulatory system
Research Abstract

In order to discuss a selection criteria for surgical technique on cardiovascular diseases, it is effective to make use of a mock circulatory system. In this study, mitral regurgitation is focused for the development of surgical training simulator. At first reproduction of mitral regurgitation was achieved. Then quantitative evaluation of the mitral valvuloplasty were performed as an application of the in vitro simulator.
1.Reproduction of mitral regurgitation
A fresh porcine mitral valve with chordae and papillary muscles was installed into the mitral position of the mock circuit. The evaluation system is capable of simulating various mitral conditions by changing the valve orientation. The normal model was implemented with the papillary muscle in the same configuration as in a natural heart. In contrast, the prolapse model was produced by severing anterior marginal chordae. As a result, valve closure similar to a natural heart was successfully attained in the normal model.
2.Evaluation of the effectiveness of mitral valvuloplasty
A comparative test was conducted to evaluate the effectiveness of mitral valvuloplasty techniques for the repair of an anterior mitral leaflet prolapse. In order to correct the prolapsed portion of mitral valve, the chordal replacement (replacement model) and the edge-to-edge technique (Edge-to-Edge model) were applied by an experienced surgeon. After the application of the two, the prolapsed portion was corrected in systole, and a double orifice area of E-to-E model was observed in diastole.
In conclusion, it has been confirmed that the mock system developed in this study can provide useful data for cardiac surgeons. As the data can be treated quantitatively, surgeons and biomedical engineers can discuss on the scientific basis.

  • Research Products

    (10 results)

All 2005 2004

All Journal Article (9 results) Patent(Industrial Property Rights) (1 results)

  • [Journal Article] 循環シミュレータによる人工弁輪の医工学的評価2005

    • Author(s)
      梅津光生, 加瀬川均, 土井博文, 野田怜子, 平山智博
    • Journal Title

      人工臓器 34・2

      Pages: 175

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Assessment of mitral surgical corrections using an in vitro Mock circulatory system2005

    • Author(s)
      M.Umezu, M.Makoto, H.Kasegawa, H.Doi, R.Noda, T.Hirayama
    • Journal Title

      IFMBE Proceedings 12

      Pages: 1A-04

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Assessment of mitral surgical corrections using an in vitro Mock circulatory system2005

    • Author(s)
      M.Umezu, M.Arita, H.Kasegawa H.Doi, R.Noda, T.Hirayama
    • Journal Title

      IFMBE Proceedings 12

      Pages: 1A-04

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] 血液循環モデルの人工臓器評価への応用2004

    • Author(s)
      梅津光生, 岩崎清隆, 白石泰之他
    • Journal Title

      生体医工学 42

      Pages: 412

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Biomedical engineering analysis on the effectiveness of cardiovascular surgery : Anastomosis methods for coronary artery bypass grafting2004

    • Author(s)
      M.Umezu, J.Kawai, J.Suehiro, et al.
    • Journal Title

      7^<th> Polish-Japanese seminar on new technologies for future artificial ograns 7

      Pages: 26-27

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] 僧帽弁手術をサポートする血液循環シミュレータの開発2004

    • Author(s)
      梅津光生, 土井博文, 野田怜子他
    • Journal Title

      人工臓器 33

      Pages: 160

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Biomedical engineering approach to evaluate anastomosis methods for coronary artery bypass grafting2004

    • Author(s)
      M.Umezu, J.Kawai, M.Arita et al.
    • Journal Title

      Journal of Shanghai University(Natural Science) 10

      Pages: 25-28

    • Description
      「研究成果報告書概要(和文)」より
  • [Journal Article] Biomedical engineering analysis on the effectiveness of cardiovascular surgery : Anastomosis methods for coronary artery bypass grafting2004

    • Author(s)
      M.Umezu, J.Kawai, J.Suehiro, et al.
    • Journal Title

      7^<th> Polish-Japanese seminar on new technologies for future artificial organs 7

      Pages: 26-27

    • Description
      「研究成果報告書概要(欧文)」より
  • [Journal Article] Biomedical engineering approach to evaluate anastomosis methods for coronary artery bypass grafting2004

    • Author(s)
      M.Umezu, J.Kawai, M.Arita et al.
    • Journal Title

      Journal of Shanghai University (Natural Science) 10

      Pages: 25-28

    • Description
      「研究成果報告書概要(欧文)」より
  • [Patent(Industrial Property Rights)] 血液シミュレータ及び流れ変換装置2004

    • Inventor(s)
      梅津光生, 白石泰之, 有田誠也他
    • Industrial Property Rights Holder
      学校法人早稲田大学
    • Industrial Property Number
      産学官280-6
    • Filing Date
      2004-11-26
    • Description
      「研究成果報告書概要(和文)」より

URL: 

Published: 2007-12-13  

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