2017 Fiscal Year Final Research Report

Central neural circuits responsible for generating central command during exercise

Research Project

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Project/Area Number	15H03061
Research Category	Grant-in-Aid for Scientific Research (B)
Allocation Type	Single-year Grants
Section	一般
Research Field	Developmental mechanisms and the body works
Research Institution	Hiroshima University
Principal Investigator	MATSUKAWA KANJI 広島大学, 医歯薬保健学研究科(保), 教授 (90165788)
Co-Investigator(Kenkyū-buntansha)	丹信介山口大学, 教育学部, 教授 (00179920) 小峰秀彦国立研究開発法人産業技術総合研究所, 情報・人間工学領域, 研究チーム長 (10392614) 定本朋子日本女子体育大学, 体育学部, 教授 (30201528) 長尾正崇広島大学, 医歯薬保健学研究科(医), 教授 (80227991) 相澤秀紀広島大学, 医歯薬保健学研究科(医), 教授 (80391837) 川真田聖一広島大学, 医歯薬保健学研究院(保), 教授 (30127641)
Co-Investigator(Renkei-kenkyūsha)	LIANG Nan 広島大学, 大学院医歯薬保健学研究科, 助教 (70512515) ENDO Kana 広島大学, 大学院医歯薬保健学研究科, 助教 (60584696) KUROSE Tomoyuki 広島大学, 大学院医歯薬保健学研究科, 助教 (20363054)
Research Collaborator	ISHII Kei , 学振PD特別研究員 ASAHARA Ryota , 学振PD特別研究員 IDESAKO Mitsuhiro 広島大学, 大学院生
Project Period (FY)	2015-04-01 – 2018-03-31
Keywords	随意運動 / 運動の精神イメージ / 筋交感神経と筋血流量 / 交感神経コリン作動性血管拡張 / セントラルコマンドの発現 / 大脳皮質前頭前野 / 大脳皮質運動野 / 中枢神経機構
Outline of Final Research Achievements	We have found using near-infrared spectroscopy that prefrontal oxygenated- hemoglobin (Oxy-Hb) concentration, measured as index of regional cerebral blood flow, increased 5-10 s prior to the onset of arbitrary ergometer exercise in a laboratory and freely-moving walking on the floor. Such increase in prefrontal Oxy-Hb was, however, absent when exercise was abruptly started by a verbal cue. The increase in prefrontal Oxy-Hb observed prior to the onset of voluntary exercise was early enough for autonomic control of the cardiovascular system at the onset of voluntary exercise. Mental imagery of the overground walking incresaed prefrofontal oxygenation to the same exent as in the case of actual walking. Thus it is suggested that the prefrontal cortex may play a role in contributing to generation of central command.
Free Research Field	自律神経生理学・循環生理学・運動生理学