Lipid immunity in rhesus monkeys and development of a new anti-tuberculosis vaccine

2017 Fiscal Year Final Research Report

• Project/Area Number: 15H04869
• Research Category: Grant-in-Aid for Scientific Research (B)
• Allocation Type: Single-year Grants
• Section: 一般
• Research Field: Infectious disease medicine
• Research Institution: Kyoto University
• Principal Investigator: SUGITA Masahiko 京都大学, ウイルス・再生医科学研究所, 教授 (80333532)
• Co-Investigator(Kenkyū-buntansha): 中村 孝司 北海道大学, 薬学研究院, 助教 (20604458)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 結核 / 脂質ワクチン

Outline of Final Research Achievements

Tuberculosis remains to be a global threat to humans. The only currently available anti-tuberculosis vaccine, BCG, has been used for decade, but development of alternative vaccines is definitely required. The principal investigator has attempted to develop a new type of lipid-based vaccines against tuberculosis. In this study, the vaccine candidate lipid was studied extensively in terms of is biosynthesis as well as its immunological properties. The findings obtained in this study provide an important basis for the development of anti-tuberculosis lipid vaccines.

Free Research Field

感染免疫