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2017 Fiscal Year Final Research Report

MEMS for electron microscopy to study nanobiology and its application to observation of bacterial dynamics

Research Project

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Project/Area Number 15H05416
Research Category

Grant-in-Aid for Young Scientists (A)

Allocation TypeSingle-year Grants
Research Field Nano/Microsystems
Research InstitutionTokyo Institute of Technology

Principal Investigator

Ishida Tadashi  東京工業大学, 工学院, 准教授 (80517607)

Research Collaborator OHNO Teruaki  テクネックス工房, 技術者
KAKUSHIMA Kuniyuki  東京工業大学, 工学院, 准教授 (50401568)
OMATA Tatsuo  名古屋大学, 生命農学研究科, 教授 (50175270)
TAKATANI Nobuyuki  名古屋大学, 生命農学研究科, 研究員
Project Period (FY) 2015-04-01 – 2018-03-31
KeywordsMEMS / 電子顕微鏡 / 液体セル / 細菌 / 動態観察
Outline of Final Research Achievements

Although specimens should normally be placed in vacuum condition for electron microscopes, we developed micro-electro-mechanical systems to visualize in-liquid bacteria. In this project, we developed a specimen holder to control cell cultural conditions, and a microfluidic device with a electron transparent membrane which separate vacuum and liquid. By using them, we visualized the dynamic motions of bubbles in liquid and droplets on the membrane, and observed cyanobacteria under cultural condition for long time.

Free Research Field

MEMS

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Published: 2019-03-29  

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