Identification and function analysis of susceptible genes for familial pulmonary NTM diseases

2016 Fiscal Year Final Research Report

• Project/Area Number: 15H06590
• Research Category: Grant-in-Aid for Research Activity Start-up
• Allocation Type: Single-year Grants
• Research Field: Respiratory organ internal medicine
• Research Institution: Keio University
• Principal Investigator: Namkoong Ho 慶應義塾大学, 医学部(信濃町), 助教 (50594644)
• Project Period (FY): 2015-08-28 – 2017-03-31
• Keywords: エクソーム解析 / 肺NTM症 / 疾患感受性遺伝子

Outline of Final Research Achievements

We have gathered DNA samples from 21 Japanese cases of familial PNTM disease（10 families）. We have performed exome analysis for the family members who were suspected to have the strong susceptible gens since the three members suffered from pulmonary NTM diseases. Concretely, after SNP analysis, we have confirmed gene A by the sanger sequencing.

Free Research Field

呼吸器感染症