2017 Fiscal Year Final Research Report
Skin tissue bud formation by in vitro self-organization approach
| Project/Area Number |
15K01303
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Biomedical engineering/Biomaterial science and engineering
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| Research Institution | Okayama University of Science |
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Principal Investigator |
Kataoka Ken 岡山理科大学, 理学部, 教授 (10293317)
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| Co-Investigator(Kenkyū-buntansha) |
辻極 秀次 岡山理科大学, 理学部, 教授 (70335628)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 附属器原基 / 培養皮膚 |
|---|
| Outline of Final Research Achievements |
Human mesenchymal stem cells, human endothelial cells, mouse skin dermal cells and epidermal cells were cultured with/without mouse macrophages on Matrigel-coated culture plates in vitro. Inoculated cells were aggregated and formed spheroids with layers. When the spheroids were transplanted on the back of immune-deficient mice, very few fair follicles were observed at the transplantation site.
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| Free Research Field |
再生医学
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