Distribution of essential trace elements in deciduous and permanent teeth, its relationship with general health condition of children

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K01746
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Childhood science (childhood environment science)
• Research Institution: Tohoku University
• Principal Investigator: IGARI Kazuko 東北大学, 大学病院, 講師 (90125493)
• Co-Investigator(Kenkyū-buntansha): 高橋 温 東北大学, 大学病院, 助教 (50333828) ; 松山 成男 東北大学, 工学研究科, 教授 (70219525)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 必須微量元素分析 / 乳歯 / 永久歯 / PIXE法 / 子どもの健康

Outline of Final Research Achievements

Zinc (Zn) and copper (Cu) are essential trace elements and important for the development of the brain function. This study aimed to investigate the distribution of these trace elements in the teeth and evaluate its relationship with general conditions of the perinatal period. The low Zn/Cn ratio and relatively low concentrations of Zn were showed in the pre- and postnatal enamel of the deciduous teeth from children with neonatal asphyxia and/or low birth weight. Also, the low concentration of Zn in the dentin was observed in the deciduous tooth from the extremely-low-birth-weight infant. The distributions of Cu were almost same in both enamel and dentin of all teeth. It was suggested that there was a relationship between low birth weight and the deficiency of Zn intake.

Free Research Field

社会系歯学（障害者歯科学）