Non-average structure of particles in liquid studied by fast single-particle analysis using femtosecond X-ray pulses

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K05407
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Physical chemistry
• Research Institution: Japan Synchrotron Radiation Research Institute
• Principal Investigator: Tono Kensuke 公益財団法人高輝度光科学研究センター, XFEL利用研究推進室, 主幹研究員 (00353508)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: X線自由電子レーザー / X線構造解析 / X線回折

Outline of Final Research Achievements

Function analysis of biological materials has been performed at the SPring-8 Angstrom Compact Free Electron Laser (SACLA) by using a newly developed experimental system for obtaining dynamical structure of micrometer-scale particles. A pulsed droplet injector was developed as an efficient sample delivery tool in the experimental system, which was successfully applied to the structure analysis of small protein crystals. By combining with an optical laser, this system was able to capture structural dynamics of photo-responsive protein. These studies demonstrate that the new experimental system is highly useful for function analysis of materials.

Free Research Field

物理化学