Development of optical detection method for biomolecules by utilizing inorganic nanosheets

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K05542
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Analytical chemistry
• Research Institution: Saga University
• Principal Investigator: SOH Nobuaki 佐賀大学, 農学部, 教授 (90336008)
• Co-Investigator(Renkei-kenkyūsha): KAMADA Kai 長崎大学, 大学院工学研究科, 准教授 (90315284)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 無機ナノシート / 酵素 / 蛍光 / バイオ材料

Outline of Final Research Achievements

In this study, we tried to develop fluorescence detection method for biomolecules by utilizing inorganic nanosheets. First, we developed a fluorescence detection method for hydrogen peroxide using a complex composed of europium-doped titanate nanosheets (Eu-TiOx) and horseradish peroxidase (HRP). Next, we developed a fluorescence detection method for glucose using a complex composed of Eu-TiOx, HRP, and glucose oxidase (GOx). Therefore, Eu-TiOx nanosheets were successfully applied to the development of fluorescence detection method for biomolecules.

Free Research Field

分析化学