Development of inspection system for diagnosis of infectious diseases using a compact disk-type microfluidic device

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K05544
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Analytical chemistry
• Research Institution: Tokyo Metropolitan University
• Principal Investigator: NAKAJIMA Hizuru 首都大学東京, 都市環境科学研究科, 准教授 (10432858)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: CD型マイクロチップ / マイクロ化学分析システム / 蛍光 / 酵素免疫測定法 / オンサイト測定 / POCT / 感染症

Outline of Final Research Achievements

A novel compact disk (CD)-type fluorescence detection system capable of real-time measurement was developed for rapid diagnosis of infectious diseases. This fluorescence detection system can automatically perform analytical operations including sample introduction, separation and detection on a CD-type microfluidic device by rotating a light source (LED) and a photodetector (photodiode) with the CD-type microfluidic device. A portable fluorescence detection system that could run on a battery was also developed for point of care testing (POCT). This portable fluorescence detection system was successfully used in an antibody test on infectious diseases.

Free Research Field

分析化学