Elucidating electron transfer mechanism of new [NiFe]hydrogenase surpassing platinum catalyst

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K05566
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Bio-related chemistry
• Research Institution: Kyushu University
• Principal Investigator: Ki-Seok Yoon 九州大学, カーボンニュートラル・エネルギー国際研究所, 准教授 (50701497)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 水素酸化反応 / ヒドロゲナーゼ / 酸素耐性酵素 / 燃料電池

Outline of Final Research Achievements

[NiFe]hydrogenases catalyze the reversible reaction of the cleavage and production of H2, harboring a NiFe center for H2 activation in a large subunit and iron-sulfur clusters for electron transfer in a small subunit. The H2-catalyzing biocatalysts have received much attention due to their potential applications in H2-based fuel cell technology. However, most hydrogenases are highly sensitive to O2, leading to inactivation of catalytic activity after oxidative stress. We recently found the new O2-tolerant [NiFe]hydrogenases from our isolated enterobacterium Citrobacter sp. S-77. The newly found [NiFe]hydrogenase displays an excellent performance for catalytic H2-activation as an O2-tolerant catalyst.

Free Research Field

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