2017 Fiscal Year Final Research Report
Characterization of newly identified factors acting downstream of DNA methylation in gene expression.
| Project/Area Number |
15K07100
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Plant molecular biology/Plant physiology
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| Research Institution | Nagaoka University of Technology |
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Principal Investigator |
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| Research Collaborator |
KATOH Etsuko 国立研究開発法人農業・食品産業技術総合研究機構, 高度解析センター 生体分子解析チーム, 主席研究員
Tran Hien Linh 長岡技術科学大学, 大学院生
NOGAWA Shogo 長岡技術科学大学, 工学研究科, 大学院生
YUKAWA Yusuke 長岡技術科学大学, 工学研究科, 大学院生
ARAKAKI Makoto 長岡技術科学大学, 工学研究科, 大学院生
HIRASAWA Tatsumi 長岡技術科学大学, 工学研究科, 大学院生
KUGO Takamasa 長岡技術科学大学, 工学研究科, 大学院生
HOSHINO Ami 長岡技術科学大学, 工学研究科, 大学院生
SATO Takuma 長岡技術科学大学, 工学部・学部
YAMAMOTO Marie 長岡技術科学大学, 工学部・学部
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 遺伝子サイレンシング / DNAメチル化 / シロイヌナズナ |
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| Outline of Final Research Achievements |
MOM1, a silencing factor in Arabidopsis thaliana, is predicted to act downstream of DNA methylation in gene expression due to the phenotype of its loss of function mutants. By genetic and biochemical approaches, we identified new factors which function in the same pathway as MOM1 in gene regulation. Since the factors involved in addition or elimination of SUMO, which is one of protein modifications, were included among them, we hypothesized that SUMOylation in some proteins would be important as a downstream mechanism of DNA methylation in gene expression.
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| Free Research Field |
植物分子遺伝学
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