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2018 Fiscal Year Final Research Report

Plant epigenetics: molecular mechanisms controlling gene expression and transgenerational inheritance

Research Project

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Project/Area Number 15K07118
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Plant molecular biology/Plant physiology
Research InstitutionNational Institute for Basic Biology

Principal Investigator

Hoshino Atsushi  基礎生物学研究所, 多様性生物学研究室, 助教 (80312205)

Research Collaborator SAKAKIBARA YASUBUMI  
Jayakumar Vasanthan  
NAGAKI KIYOTAKA  
MORITA YASUMASA  
NITASAKA EIJI  
ITO KAZUYO  
NAKAMURA RYOKO  
TAKEUCHI TOMOYO  
Project Period (FY) 2015-10-21 – 2019-03-31
Keywordsエピジェネティクス / 植物 / クロマチン / DNAのメチル化 / アサガオ / ヒストン / トランスポゾン
Outline of Final Research Achievements

Floral pigmentation patterns are often caused by partial suppression of genes affecting flower petal coloration. We call one of the mechanisms for such gene suppression "epigenetics." Some morning glory cultivars show flowers with particular stripes. From molecular analyses of the striped flowers, we found that DNA methylation that is a key player of epigenetics suppresses the expression of the genes for flower coloration by inhibition of interaction between DNA and a protein. In addition, it was suggested that DNA methylation is involved in transgenerational inheritance of flower pigmentation.

Free Research Field

分子遺伝学

Academic Significance and Societal Importance of the Research Achievements

エピジェネティクスは遺伝子のはたらきを調節する仕組みで、生物や細胞に個性と多様性を与えている。アサガオの刷毛目絞は、エピジェネティクスの変動が模様としてあらわれるユニークな材料である。その特性を活かして、エピジェネティクスの主要な役者であるDNAのメチル化が遺伝子を抑制し、世代を越えた遺伝にかわるメカニズムに迫ることができた。エピジェネティクスや花の模様の明快なモデルになることが期待される。

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Published: 2020-03-30  

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