2017 Fiscal Year Final Research Report
Physiological roles of relaxin in vertebrates
| Project/Area Number |
15K07125
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Morphology/Structure
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| Research Institution | Shizuoka University |
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Principal Investigator |
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| Co-Investigator(Renkei-kenkyūsha) |
MUKUDA Takao 鳥取大学, 医学部, 講師 (60346335)
KITANO Jun 国立遺伝学研究所, 集団遺伝研究系, 教授 (80346105)
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| Research Collaborator |
RAVINET Mark University of Oslo, Centre for Ecological and Evolutionary Synthesis, Researcher
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | リラキシン / イトヨ / 脳 / 量的形質遺伝子座解析 / 浸透圧調節 |
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| Outline of Final Research Achievements |
Relaxin is known as a hormone that has roles to help pregnancy and childbirth. The existence of relaxin gene has been confirmed in all vertebrates including fish. However, the functions of relaxin other than mammals are not well understood. Therefore, the function of relaxin was analyzed and the physiological significance of relaxin of teleosts was examined upon the perspective of comparative endocrinology and evolution. The sites of expression of the relaxin genes in the brain of stickleback were histologically analyzed. In order to clarify the regulatory mechanism of relaxin expression in the brain, expression mechanism of relaxin gene was analyzed by quantitative trait locus method.
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| Free Research Field |
比較内分泌学
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