2017 Fiscal Year Final Research Report
Total synthesis of fused heterocyclic natural products utilizing microwaves and search for drug discovery molecules
| Project/Area Number |
15K07880
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Chemical pharmacy
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| Research Institution | Fukuyama University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
波多江 典之 北海道医療大学, 薬学部, 准教授 (30449912)
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| Research Collaborator |
NISHIYAMA Takashi
HIRONAKA Miharu
TANINAKA Kimiko
OBATA Manami
TAKAIWA Shuuya
MURAKAMI Mari
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 電子環状反応 / マイクロ波 / 縮合複素環 / Azafluorenone / Protoberberine / Pyrrolo[2,3-c]quinoline |
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| Outline of Final Research Achievements |
It was utilized as a key reaction for the core structure construction of heterocyclic natural products targeting two synthetic methods and was developed to total synthesis. We also conducted activity evaluation using a series of novel compounds, and conducted search research on drug target molecules.
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| Free Research Field |
有機合成化学
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