Effects of surface contamination on antibacterial activity of antibacterial metals

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K08852
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Medical and hospital managemen
• Research Institution: Osaka City University
• Principal Investigator: Kawakami Hiroshi 大阪市立大学, 大学院工学研究科, 准教授 (90305615)
• Co-Investigator(Kenkyū-buntansha): 佐藤 嘉洋 大阪市立大学, 大学院工学研究科, 教授 (00170796)
• Co-Investigator(Renkei-kenkyūsha): Wang Pengyuan ; KATO Hisashi ; KIKUCHI Yasushi ; SUZUKI Satoshi ; TAKASHIMA Yuta ; TODA Yuzo ; HIRAYAMA Kenta
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: 抗菌性金属材料 / 銅合金 / 表面汚損 / 院内感染対策 / 食中毒対策

Outline of Final Research Achievements

In this study, effects of i) surface contamination and ii) cleaning agents on antibacterial activities, and iii) effective cleaning methods for recovering the antibacterial activities of copper alloys, which were degraded by surface contamination, were studied. When the triolein contaminated surfaces were wiped clean with ethanol or 0.05 mass% sodium hypochlorite aq., the degraded antibacterial activities recovered to levels close to those with clean surfaces. For protein surface contamination, one cycle of wipe cleaning with sodium hypochlorite aq. did not result in complete recovery of degraded antibacterial activities. It is necessary to develop measure to prevent antibacterial metals from surface deterioration caused by cleaning agents.

Free Research Field

機械材料学