2017 Fiscal Year Final Research Report
Biomarker analysis with next generation sequencer in pulmonary sarcomatoid carcinomas
| Project/Area Number |
15K09164
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Respiratory organ internal medicine
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| Research Institution | Hokkaido University |
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Principal Investigator |
OIZUMI SATOSHI 北海道大学, 医学研究院, 客員研究員 (10421968)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 肺肉腫様癌 |
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| Outline of Final Research Achievements |
Efficacy of chemotherapy or presence of targetable genomic alterations has remained unclear in pulmonary sarcomatoid carcinomas. Development of therapeutic strategies for this entity is an important issue.
Biomarker analysis is being conducted with next generation sequencer in parallel with our prospective phase 2 study which prospectively examines the efficacy of chemotherapy in pulmonary sarcomatoid carcinomas.
So far 15 patients have been enrolled onto this study (target patient number; 30), and we are conducting the biomarker analysis employing the tissue materials from the enrolled patients.
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| Free Research Field |
呼吸器内科学
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