2017 Fiscal Year Final Research Report
Brain connectome change associated with propagation of amyloid beta in Alzheimer's disease.
Project/Area Number |
15K09353
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Research Category |
Grant-in-Aid for Scientific Research (C)
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Allocation Type | Multi-year Fund |
Section | 一般 |
Research Field |
Neurology
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Research Institution | Kyushu University |
Principal Investigator |
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Co-Investigator(Kenkyū-buntansha) |
上原 平 九州大学, 医学研究院, 助教 (30631585)
|
Project Period (FY) |
2015-04-01 – 2018-03-31
|
Keywords | アルツハイマー病 / 安静時機能的MRI / 脳コネクトーム |
Outline of Final Research Achievements |
This study aimed to elucidate asscoation brai connectome change and paropagation of beta amyloid protein. We revealed the assciation impairment of orientation for time and dysconnection from posterior cingulate gyrus to riht middle temporal gyrus. We intended to elucidate the relation functional connectivity change and pathologoical change associated with other higer fuction including memory impairment. furthermore we will investigate the pathlogivcal change according to the connectome of AD using PET in future.
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Free Research Field |
神経内科学
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