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2017 Fiscal Year Final Research Report

Brain connectome change associated with propagation of amyloid beta in Alzheimer's disease.

Research Project

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Project/Area Number 15K09353
Research Category

Grant-in-Aid for Scientific Research (C)

Allocation TypeMulti-year Fund
Section一般
Research Field Neurology
Research InstitutionKyushu University

Principal Investigator

Yamashita Kenichiro  九州大学, 大学病院, 助教 (00596687)

Co-Investigator(Kenkyū-buntansha) 上原 平  九州大学, 医学研究院, 助教 (30631585)
Project Period (FY) 2015-04-01 – 2018-03-31
Keywordsアルツハイマー病 / 安静時機能的MRI / 脳コネクトーム
Outline of Final Research Achievements

This study aimed to elucidate asscoation brai connectome change and paropagation of beta amyloid protein. We revealed the assciation impairment of orientation for time and dysconnection from posterior cingulate gyrus to riht middle temporal gyrus. We intended to elucidate the relation functional connectivity change and pathologoical change associated with other higer fuction including memory impairment. furthermore we will investigate the pathlogivcal change according to the connectome of AD using PET in future.

Free Research Field

神経内科学

URL: 

Published: 2019-03-29  

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