2017 Fiscal Year Final Research Report
Complex energy absorption process analysis by lipidomics
| Project/Area Number |
15K09401
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Metabolomics
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| Research Institution | Tokyo University of Pharmacy and Life Science |
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Principal Investigator |
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | エネルギー・糖質代謝異常 / 膜輸送と輸送タンパク質 / リピドミクス |
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| Outline of Final Research Achievements |
Among omics methods for the quantification/qualification of biological substances, this study is oriented to clarify the mechanisms for the intestinal energy absorption by lipidomics. By selecting nineteen types of lipid as analytes, a new lipidomics method was developed by liquid chromatography ion-trap time-of-flight mass spectrometry (LC-IT-TOF-MS). Real sample analysis showed that linoleic acid, lysophosphatidylcholines, phosphatidylcholines and triacylglycerols in enteral nutrition Twinline were detected by LC-IT-TOF-MS.
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| Free Research Field |
分析化学／生化学
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