2017 Fiscal Year Final Research Report
Critical factors for the neonatal bronchopulmonary dysplasia, and development of the inflammation-specific therapeutic strategies
| Project/Area Number |
15K09717
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Embryonic/Neonatal medicine
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| Research Institution | Kyushu University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
井上 普介 九州大学, 大学病院, その他 (90467902)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | 新生児 / 周産期 / 早産児 / 呼吸器 |
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| Outline of Final Research Achievements |
The pathophysiology of neonatal bronchopulmonary dysplasia (BPD) involves underlying multi-factors including immaturity of the fetal lung, oxygen toxicity, baro-/volu-trauma and inflammatory mediators. We previously established “Kyushu University High-Risk Neonatal Clinical Research Network” to conduct a multicenter cohort study. In addition, a new scoring system of chest computed tomography was reported to assess the clinical severity of BPD. We here investigated clinical and biochemical factors associated with the severity of BPD, based on the research platform. The future plans were the biotrauma-specific randomized controlled trials for the high-risk patients, and the inflammation-specific therapeutic strategies.
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| Free Research Field |
新生児医療
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