T1 rho map analysis for the evaluation of early hepatic fibrosis

2017 Fiscal Year Final Research Report

• Project/Area Number: 15K09918
• Research Category: Grant-in-Aid for Scientific Research (C)
• Allocation Type: Multi-year Fund
• Section: 一般
• Research Field: Radiation science
• Research Institution: Gifu University
• Principal Investigator: Goshima Satoshi 岐阜大学, 医学部附属病院, 准教授 (90402205)
• Co-Investigator(Kenkyū-buntansha): 河合 信行 岐阜大学, 医学部附属病院, 助教 (20724561) ; 渡邊 春夫 岐阜大学, 大学院医学系研究科, 非常勤講師 (30456529) ; 野田 佳史 岐阜大学, 医学部附属病院, 助教 (60643020) ; 兼松 雅之 岐阜大学, 医学部附属病院, 准教授 (40252134)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: MRI / 肝臓 / T1rho

Outline of Final Research Achievements

We applied newly advanced T1 rho calculation to the evaluation of liver fibrosis on the basis of semi-quantitative analysis for high-molecular compound. We found the weak correlation between T1 rho value of the liver and Child-Pugh score and APRI, whereas the liver-to-spleen ratio of T1 rho value demonstrated a significant difference between patients with and without chronic liver damage. There was no significant differences between focal liver nodules. It is hoped that further study will be applied to analysis of glycose metabolism within the malignant tumor and liver induced jaundice.

Free Research Field

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