酸素強調心臓MRIの撮影法の開発

2016 Fiscal Year Research-status Report

• Project/Area Number: 15K09929
• Research Institution: Kyushu University
• Principal Investigator: 川波 哲 九州大学, 医学研究院, 助教 (50330999)
• Co-Investigator(Kenkyū-buntansha): 神谷 武志 九州大学, 大学病院, 助教 (20419534) ; 山之内 寅彦 九州大学, 大学病院, 医員 (40748034) [Withdrawn] ; 長尾 充展 九州大学, 医学研究院, 准教授 (60533081) [Withdrawn] ; 藪内 英剛 九州大学, 医学研究院, 教授 (70380623) ; 本田 浩 九州大学, 医学研究院, 教授 (90145433)
• Project Period (FY): 2015-04-01 – 2018-03-31
• Keywords: MRI / 心臓 / 心筋症 / 酸素 / 線維化 / 肥大型心筋症 / 拡張型心筋症 / BOLD

Outline of Annual Research Achievements

平成27年度より3年で酸素強調T2*心臓MRIの撮影方法と有用性を確立する予定である。

本年度は関連論文4編、国内学会発表3編、国外学会発表3編を報告した。とくに論文発表したQuantification of myocardial oxygenation in heart failure using blood-oxygen-level-dependent T2* magnetic resonance imaging: Comparison with cardiopulmonary exercise test. Magn Reson Imaging. 2017 Feb 17;39:138-143.については本研究の初期経験をまとめたものである。本年度は、解析用ワークステーションも最新のものとなるため、データ解析の精度を高め、さらなる論文発表を進める。

Current Status of Research Progress

2: Research has progressed on the whole more than it was originally planned.

Reason

平成27年度より国内1回、国外2回の学会発表を行った。平成28年度は1編が論文掲載された。

Strategy for Future Research Activity

解析用ワークステーションが更新されたため、これを利用して詳細な解析を行い、論文を作成予定。

Causes of Carryover

解析用ワークステーション未購入のため

Expenditure Plan for Carryover Budget

解析用ワークステーション、アプリケーションを購入予定

Research Products

• [Journal Article] Quantification of myocardial oxygenation in heart failure using blood-oxygen-level-dependent T2* magnetic resonance imaging: Comparison with cardiopulmonary exercise test. (2017)
  • Author(s): Nagao M, Yamasaki Y, Kawanami S, Kamitani T, Sagiyama K, Higo T, Ide T, Takemura A, Ishizaki U, Fukushima K, Watanabe Y, Honda H.
  • Journal Title: Magn Reson Imaging Volume: 39 Pages: 138-143
  • DOI: 10.1016/j.mri.2017.02.005
  • Peer Reviewed / Open Access / Acknowledgement Compliant
• [Journal Article] Energy efficiency and pulmonary artery flow after balloon pulmonary angioplasty for inoperable, chronic thromboembolic pulmonary hypertension: Analysis by phase-contrast MRI. (2017)
  • Author(s): Nagao M, Yamasaki Y, Abe K, Hosokawa K, Kawanami S, Kamitani T, Yamanouchi T, Yabuuchi H, Fukushima K, Honda H.
  • Journal Title: Eur J Radiol. Volume: 87 Pages: 99-104
  • DOI: 10.1016/j.ejrad.2016.12.015.
  • Peer Reviewed / Open Access
• [Journal Article] Balloon pulmonary angioplasty improves interventricular dyssynchrony in patients with inoperable chronic thromboembolic pulmonary hypertension: a cardiac MR imaging study. (2017)
  • Author(s): Yamasaki Y, Nagao M, Abe K, Hosokawa K, Kawanami S, Kamitani T, Yamanouchi T, Horimoto K, Yabuuchi H, Honda H.
  • Journal Title: Int J Cardiovasc Imaging. Volume: 33 Pages: 229-239
  • DOI: 10.1007/s10554-016-0985-y.
  • Peer Reviewed / Open Access
• [Journal Article] Clinical impact of left ventricular eccentricity index using cardiac MRI in assessment of right ventricular hemodynamics and myocardial fibrosis in congenital heart disease. (2016)
  • Author(s): Yamasaki Y, Nagao M, Kamitani T, Yamanouchi T, Kawanami S, Yamamura K, Sakamoto I, Yabuuchi H, Honda H.
  • Journal Title: Eur Radiol. Volume: 26 Pages: 3617-25
  • DOI: 10.1007/s00330-015-4199-9.
• [Presentation] Quantitative MR imaging in pulmonary hypertension: How to evaluate the hemodynamics and therapeutic effect. (2016)
  • Author(s): Yamasaki Y, Kawanami S, Kamitani T, Sagiyama K , Kamei S , Hosokawa K, Horimoto K , Abe K , Yabuuchi H, Honda H
  • Organizer: 102th Scientific Assembly and Annual Meeting of Radiological Society of North America.
  • Place of Presentation: Chicago, USA
  • Year and Date: 2016-11-27 – 2016-12-02
  • Int'l Joint Research
• [Presentation] Cardiovascular CT and MR imaging in adult congenital heart disease: A practical approach to the current state of the art. (2016)
  • Author(s): Yamasaki Y, Kawanami S, Kamitani T, Sagiyama K, Kamei S, Yamamura K, Sakamoto I, Yabuuchi H, Honda H.
  • Organizer: 102th Scientific Assembly and Annual Meeting of Radiological Society of North America.
  • Place of Presentation: Chicago, USA
  • Year and Date: 2016-11-27 – 2016-12-02
  • Int'l Joint Research
• [Presentation] Oxygen-enhanced cardiac magnetic resonance imaging in cardiomyopathy. (2016)
  • Author(s): Kawanami S, Nagao M, Yamasaki Y, Kamitani T, Yamanouchi T, Yuko Tanaka, Yabuuchi H, Ide T, Funatsu R, Watanabe Y, Honda H.
  • Organizer: 1.24th Annual Meeting International Society for Magnetic Resonance in Medicine.
  • Place of Presentation: Singapore
  • Year and Date: 2016-05-07 – 2016-05-13
  • Int'l Joint Research