2017 Fiscal Year Final Research Report
Chronic inflammation and sarcopenia in radiotherapy for cancer: novel prognosticators over chronological age
| Project/Area Number |
15K09992
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| Research Category |
Grant-in-Aid for Scientific Research (C)
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| Allocation Type | Multi-year Fund |
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| Section | 一般 |
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| Research Field |
Radiation science
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| Research Institution | Kyoto University |
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Principal Investigator |
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| Co-Investigator(Kenkyū-buntansha) |
中村 晶 京都大学, 医学研究科, 助教 (40708591)
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| Project Period (FY) |
2015-04-01 – 2018-03-31
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| Keywords | サルコペニア / 慢性炎症 / 放射線治療 / がん治療 |
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| Outline of Final Research Achievements |
We evaluated relationship of chronic inflammation and sarcopenia with survival outcomes after radiotherapy for cancer. In patients treated with stereotactic body radiotherapy for early stage lung cancer, chronic inflammation and sarcopenia were respectively associated with lung cancer death and non-lung cancer death. Patients with locally-advanced lung cancer with chronic inflammation and lower body mass index had poorer prognosis. The results suggested that chronic inflammation and sarcopenia can be novel prognosticators over chronological age or tumor stage.
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| Free Research Field |
放射線腫瘍学
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